| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
I-BET 151 Hydrochloride is a selective inhibitor of bromodomain-containing proteins, showcasing a unique ability to disrupt protein-protein interactions critical for gene regulation. Its structure facilitates specific hydrogen bonding and hydrophobic interactions, enhancing binding affinity. The hydrochloride form improves solubility, promoting effective cellular uptake. Additionally, its kinetic behavior indicates a sustained engagement with target proteins, influencing epigenetic modulation and transcriptional activity. | ||||||
GSK 525762A | 1260907-17-2 | sc-490339 sc-490339A sc-490339B sc-490339C sc-490339D | 5 mg 10 mg 50 mg 100 mg 1 g | $300.00 $540.00 $940.00 $1680.00 $5900.00 | ||
GSK 525762A is a potent bromodomain inhibitor that exhibits remarkable selectivity through its unique binding profile. Its molecular architecture allows for specific π-π stacking and van der Waals interactions, which enhance its affinity for target proteins. The compound's dynamic behavior in solution suggests rapid conformational changes, optimizing its interaction kinetics. Furthermore, its lipophilic characteristics contribute to membrane permeability, facilitating cellular access and engagement with bromodomain targets. | ||||||