The chemical class of SLC22A17 Activators includes compounds that can indirectly influence the activity of SLC22A17 through their effects on iron metabolism, cellular uptake mechanisms, and related signaling pathways. These compounds do not directly activate SLC22A17; instead, they modulate cellular environments or pathways that could enhance SLC22A17's functional role in iron transport.
Compounds such as Deferoxamine, Ferric Ammonium Citrate, and Lactoferrin directly influence iron homeostasis, potentially impacting SLC22A17's iron transport function. Antioxidants like Curcumin, Resveratrol, EGCG, Quercetin, and N-Acetylcysteine could modulate oxidative stress and iron metabolism, thereby influencing SLC22A17 activity. Vitamin D, Zinc, and Retinoic Acid, known for their roles in cellular function regulation and metal homeostasis, might also indirectly affect SLC22A17. Sodium Butyrate, by altering gene expression, could also impact the function of SLC22A17 in iron metabolism.
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