Date published: 2026-5-16

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ANKRD60 Activators

ANKRD60, or Ankyrin Repeat Domain 60, is a protein encoded by the ANKRD60 gene. As a member of the ankyrin repeat protein family, ANKRD60 features a series of ankyrin repeats, which are known for mediating protein-protein interactions. These repeats consist of approximately 33 amino acids and are involved in a wide range of cellular processes, including signal transduction, cell cycle regulation, and the maintenance of cellular structure.The precise biological functions of ANKRD60 remain less defined compared to other well-studied ankyrin repeat proteins. However, based on the structural domain it possesses, ANKRD60 is likely to participate in molecular recognition events that facilitate the assembly of protein complexes. These interactions can play significant roles in the regulation of various cellular pathways, contributing to the dynamic regulation of cellular activities in response to environmental or intracellular cues.

Proteins like ANKRD60 often serve as scaffolding molecules that bring together other proteins to form functional complexes. They can be involved in the regulation of transcription factors, the organization of the cytoskeleton, and the modulation of enzymes and receptors that are pivotal to cell signaling.The expression patterns of ANKRD60, its interaction networks, and possible post-translational modifications would offer a deeper understanding of its functional implications within the cell. It is not uncommon for proteins containing ankyrin repeats to be implicated in human diseases when their normal functions are disrupted, leading to issues such as developmental abnormalities, cancer, or other genetic disorders.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, potentially affecting proteins in cAMP-dependent signaling pathways.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Activates protein kinase C (PKC), possibly influencing proteins linked with PKC signaling pathways.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Raises intracellular calcium levels, potentially impacting calcium-sensitive proteins and pathways.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Acts as a calcium ionophore, affecting intracellular calcium and possibly influencing calcium-binding proteins.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Inhibits SERCA, leading to increased cytosolic calcium, potentially affecting calcium-mediated pathways.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Inhibits N-linked glycosylation, possibly affecting protein folding and stability.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Inhibits proteasome activity, affecting protein degradation pathways.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase, potentially influencing stress response signaling pathways.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits PI3K, impacting cell survival, growth, and other signaling pathways.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibits MEK, affecting the MAPK/ERK pathway involved in cell proliferation and differentiation.