Date published: 2025-12-7

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Anaphase Promoting Complex Inhibitors

Santa Cruz Biotechnology now offers a broad range of Anaphase Promoting Complex Inhibitors for use in various applications. Anaphase Promoting Complex (APC) inhibitors are a vital category of chemicals that play a crucial role in the study of cell cycle regulation, particularly in the understanding of mitosis and cell division. The APC is an essential ubiquitin ligase that targets specific cell cycle proteins for degradation, thereby controlling the progression from metaphase to anaphase and ensuring the proper segregation of chromosomes. By inhibiting the APC, researchers can block the degradation of these key regulatory proteins, allowing for the detailed investigation of the mechanisms that govern cell cycle transitions. This makes APC inhibitors invaluable tools for studying the timing, regulation, and fidelity of chromosome separation during mitosis. Furthermore, these inhibitors are extensively used in research focused on the identification of new components of the cell cycle machinery and the exploration of the molecular signals that trigger anaphase onset. In addition, APC inhibitors help scientists dissect the complex networks of protein interactions that are critical for maintaining genomic stability and preventing aneuploidy, which is a hallmark of various cellular disorders. The application of these inhibitors extends to studies of cell cycle checkpoints, where they are used to analyze how cells respond to DNA damage and other cellular stressors that impact mitosis. Overall, Anaphase Promoting Complex Inhibitors are indispensable in advancing our understanding of cell division and the intricate control mechanisms that ensure accurate cell proliferation. View detailed information on our available Anaphase Promoting Complex Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-4-Tosyl-L-arginine methyl ester hydrochloride

1784-03-8sc-207949
sc-207949A
5 g
25 g
$40.00
$118.00
1
(0)

N-4-Tosyl-L-arginine methyl ester hydrochloride serves as a potent modulator of the Anaphase Promoting Complex, influencing cell cycle regulation. Its tosyl group enhances binding affinity to target proteins, facilitating specific molecular interactions that drive ubiquitination processes. The compound's unique structure promotes efficient substrate recognition, impacting reaction kinetics and the timing of chromosomal segregation. This specificity underscores its role in orchestrating cellular division dynamics.