ALDH1A1 Activators
Common ALDH1A1 Activators include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, Disulfiram CAS 97-77-8, Resveratrol CAS 501-36-0, D,L-Sulforaphane CAS 4478-93-7 and Omeprazole CAS 73590-58-6.
ALDH1A1 (Aldehyde Dehydrogenase 1 Family Member A1) activators are compounds or molecules that enhance the activity or function of the ALDH1A1 enzyme. ALDH1A1 is a member of the aldehyde dehydrogenase enzyme family, which plays a crucial role in the oxidation of aldehydes, converting them into less reactive carboxylic acids. ALDH1A1, in particular, is primarily involved in the oxidation of retinaldehyde to form retinoic acid, a biologically active form of vitamin A. This enzymatic reaction is a key step in the biosynthesis of retinoic acid, which, in turn, serves as a critical regulator of various cellular processes, including cell growth, differentiation, and gene expression. ALDH1A1 activators are of great interest in the field of cell biology and pharmacology as they have the potential to modulate retinoic acid production and its downstream effects on cellular physiology.
Research on ALDH1A1 activators aims to understand how these compounds interact with the ALDH1A1 enzyme and how they influence its enzymatic activity. By enhancing ALDH1A1 activity, these activators can increase the production of retinoic acid within cells, leading to alterations in cellular processes controlled by retinoic acid signaling. This can have broad implications for the fields of development, regeneration, and disease, as retinoic acid is a critical signaling molecule involved in embryonic development, tissue regeneration, and the regulation of various genes. However, it's important to note that while research in this area is promising, the development of ALDH1A1 activators for specific applications is an ongoing area of study and may require further exploration.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid signaling can modulate ALDH1A1 expression, as ALDH1A1 is involved in the synthesis of retinoic acid from retinaldehyde. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences various pathways in cells. It might modulate ALDH1A1 expression indirectly via its effects on cell survival and oxidative stress. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Induces detoxification enzymes. It might upregulate ALDH1A1 expression as a part of the cellular adaptive response to oxidative stress. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Antidiabetic suggested compound that might influence ALDH1A1 expression indirectly via AMPK activation and mTOR signaling. | ||||||
Omeprazole | 73590-58-6 | sc-202265 | 50 mg | $67.00 | 4 | |
A proton pump inhibitor that can modulate ALDH1A1 expression, potentially related to changes in cellular pH or other indirect mechanisms. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
DNA methyltransferase inhibitor that can reactivate the expression of silenced genes, potentially influencing ALDH1A1 expression by modulating epigenetic marks. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
HDAC inhibitor that may influence ALDH1A1 expression by altering chromatin structure and promoting gene expression. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $28.00 $79.00 $165.00 | 32 | |
An isoflavone that might modulate ALDH1A1 expression, potentially through interactions with estrogen receptors. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Another isoflavone that can influence ALDH1A1 expression, potentially by modulating estrogen receptor signaling. | ||||||
3,3′-Diindolylmethane | 1968-05-4 | sc-204624 sc-204624A sc-204624B sc-204624C sc-204624D sc-204624E | 100 mg 500 mg 5 g 10 g 50 g 1 g | $37.00 $65.00 $89.00 $421.00 $681.00 $66.00 | 8 | |
A compound found in the digestion of indole-3-carbinol, found in cruciferous vegetables. It might modulate ALDH1A1 expression through various cellular pathways. | ||||||