Adenosine A Receptor Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Theobromine | 83-67-0 | sc-203296 sc-203296A | 25 g 100 g | $42.00 $89.00 | ||
Theobromine acts as a selective antagonist at adenosine A receptors, exhibiting unique binding characteristics that disrupt adenosine-mediated signaling. Its molecular structure allows for specific steric interactions, leading to altered receptor conformations. Theobromine's kinetic profile reveals a moderate binding affinity, resulting in a balanced modulation of receptor activity. Additionally, its lipophilic nature enhances membrane interaction, influencing its distribution and potential impact on cellular signaling pathways. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline functions as a non-selective antagonist at adenosine A receptors, characterized by its ability to stabilize receptor states and modulate downstream signaling cascades. Its unique molecular architecture facilitates diverse interactions with receptor sites, promoting altered ligand-receptor dynamics. Theophylline exhibits a rapid dissociation rate, contributing to its transient effects on receptor activity. Furthermore, its hydrophilic properties influence solubility and permeability, affecting its interaction with cellular membranes. | ||||||
CGS 15943 | 104615-18-1 | sc-203544 sc-203544A | 10 mg 50 mg | $89.00 $406.00 | 4 | |
CGS 15943 acts as a selective antagonist at adenosine A receptors, exhibiting a unique binding affinity that enhances its interaction with specific receptor subtypes. Its structural configuration allows for distinct conformational changes upon binding, influencing receptor activation pathways. The compound demonstrates a slower dissociation rate compared to other antagonists, leading to prolonged receptor occupancy. Additionally, its lipophilic characteristics enhance membrane penetration, impacting cellular signaling processes. | ||||||
1,3,9-Trimethylxanthine | 519-32-4 | sc-216142 sc-216142A | 100 mg 500 mg | $317.00 $525.00 | ||
1,3,9-Trimethylxanthine functions as a competitive antagonist at adenosine A receptors, characterized by its ability to modulate receptor activity through specific hydrogen bonding interactions. Its unique three-dimensional structure facilitates selective binding, influencing downstream signaling cascades. The compound exhibits rapid kinetics, allowing for swift receptor engagement and disengagement, which can alter cellular responses. Its amphipathic nature enhances solubility in biological membranes, affecting bioavailability and interaction dynamics. | ||||||
SCH 58261 | 160098-96-4 | sc-204272 sc-204272A | 10 mg 50 mg | $195.00 $825.00 | ||
SCH 58261 is a selective antagonist of the adenosine A2A receptor, distinguished by its unique binding affinity that stabilizes the receptor in an inactive conformation. This compound engages in specific hydrophobic interactions and π-π stacking with aromatic residues, influencing receptor conformation and downstream signaling pathways. Its kinetic profile reveals a moderate dissociation rate, allowing for sustained modulation of receptor activity, which can impact various cellular processes. The compound's lipophilic characteristics enhance its membrane permeability, facilitating effective receptor interaction. | ||||||
2-Chloro-2′,3′-O-isopropylideneadenosine-5′-N-ethylcarboxamide | 120225-75-4 | sc-209133 | 10 mg | $380.00 | ||
2-Chloro-2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide functions as a selective agonist for adenosine A receptors, showcasing unique hydrogen bonding capabilities that enhance receptor affinity. Its isopropylidene moiety contributes to steric hindrance, influencing binding specificity and receptor conformational changes. The compound's kinetic profile reveals a moderate rate of association, allowing for sustained receptor activation, which can modulate downstream signaling pathways effectively. | ||||||
1-Allyl-3,7-dimethyl-8-sulfophenylxanthine sodium salt | 149981-25-9 | sc-206126 sc-206126A | 1 mg 5 mg | $87.00 $163.00 | ||
1-Allyl-3,7-dimethyl-8-sulfophenylxanthine sodium salt acts as a potent antagonist of the adenosine A1 receptor, characterized by its ability to disrupt adenosine-mediated signaling. This compound exhibits strong electrostatic interactions due to its sulfonate group, which enhances solubility in aqueous environments. Its unique structural features allow for selective binding, influencing receptor dynamics and altering intracellular calcium levels. The compound's rapid association kinetics enable swift modulation of receptor activity, impacting various physiological responses. | ||||||
3,7-Dimethyl-1-propargylxanthine | 14114-46-6 | sc-209732 | 10 mg | $271.00 | ||
3,7-Dimethyl-1-propargylxanthine acts as a potent antagonist at adenosine A receptors, exhibiting unique steric interactions that disrupt adenosine binding. Its propargyl group introduces a distinct electronic environment, enhancing selectivity and altering receptor dynamics. The compound's rapid dissociation kinetics facilitate transient modulation of receptor activity, influencing intracellular signaling cascades. This behavior underscores its role in fine-tuning adenosine-mediated physiological responses. | ||||||