ADAT1 Activators
ADAT1 activators are largely focused on influencing the cellular environment in ways that could indirectly affect ADAT1 activity. 5-Azacytidine and Decitabine, may alter the methylation landscape of the genome, which can, in turn, affect RNA processing and modification activities including those mediated by ADAT1. These changes in epigenetic marks could influence the transcription of genes encoding components of the RNA modification machinery, thereby indirectly affecting ADAT1's function.
Vorinostat and Trichostatin A modulate chromatin structure, thereby influencing the transcription of genes involved in RNA processing and modification. These alterations in chromatin dynamics could lead to changes in the cellular concentration of substrates and cofactors necessary for ADAT1's function. Similarly, compounds like S-Adenosylmethionine, a universal methyl donor, could play a role in various methylation reactions, influencing RNA modification processes. Inosine, as substrate and product of ADAT1's action, respectively, might be involved in a feedback mechanism regulating ADAT1 activity, though this connection is more speculative.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
An inhibitor of DNA methyltransferases, potentially affecting RNA modification processes including those mediated by ADAT1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-Azacytidine, it acts as a DNA methyltransferase inhibitor, possibly influencing ADAT1 activity indirectly. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor, which can affect chromatin structure and potentially influence RNA processing enzymes including ADAT1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, it can alter chromatin dynamics, potentially impacting ADAT1 function. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
A common methyl donor in various biological processes, which may indirectly affect RNA modification pathways involving ADAT1. | ||||||
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $120.00 | 1 | |
A byproduct of polyamine synthesis, which could potentially interact with RNA modification pathways. | ||||||
Inosine | 58-63-9 | sc-295182 sc-295182A | 1 g 5 g | $59.00 $90.00 | ||
The product of ADAT1's action on RNA; its presence may provide feedback regulation on ADAT1 activity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A short-chain fatty acid and HDAC inhibitor, potentially affecting RNA processing and indirectly ADAT1. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
A form of Vitamin B3 and an inhibitor of sirtuins (a class of HDACs), which may indirectly affect ADAT1 function. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Known primarily for its use in alcohol dependence, it can also inhibit various enzymes and could indirectly influence RNA modification processes. | ||||||