Date published: 2025-10-16

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ADAM Inhibitors

Santa Cruz Biotechnology now offers a broad range of ADAM (disintegrin and metalloprotease) Proteins for use in various applications. ADAM proteins are a family of membrane-anchored proteins that play crucial roles in a wide array of cellular processes, including cell adhesion, proteolysis, and cell signaling. These proteins are characterized by their unique structure, which combines a disintegrin domain, often involved in inhibiting cell adhesion, with a metalloprotease domain, responsible for catalyzing the cleavage of specific protein substrates. In scientific research, ADAM proteins are of significant interest due to their involvement in key biological functions such as fertilization, neurogenesis, and tissue remodeling. Researchers use these proteins to explore cell-cell and cell-matrix interactions, study the regulation of signaling pathways, and understand the molecular mechanisms underlying various physiological processes. Additionally, ADAM proteins have been employed in studies focused on the modulation of immune responses and the progression of diseases related to aberrant cellular communication. Their role in processing and shedding of cell surface proteins makes them valuable tools for investigating signal transduction and the dynamic regulation of membrane-bound molecules. By providing high-quality ADAM proteins, Santa Cruz Biotechnology supports the advancement of research in cellular biology, molecular biology, and biochemistry, enabling scientists to elucidate complex biological systems. View detailed information on our available ADAM (disintegrin and metalloprotease) Proteins by clicking on the product name.

Items 11 to 18 of 18 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Etozolin-d3 Hydrochloride

sc-497422
1 mg
$380.00
(0)

Etozolin-d3 Hydrochloride exhibits distinctive behavior as an acid halide, marked by its unique structural framework that promotes specific molecular interactions. The compound's halide functionality enhances its reactivity, enabling efficient nucleophilic attack and facilitating diverse acylation reactions. Its kinetic profile reveals a propensity for rapid transformation, allowing for selective modifications in complex synthetic pathways. The presence of multiple functional groups further enriches its reactivity landscape.

Erythrolosamine

53066-32-3sc-498341
250 mg
$268.00
1
(0)

Erythrolosamine functions as an acid halide, characterized by its unique ability to engage in selective acylation processes. Its structural features promote strong interactions with nucleophiles, leading to accelerated reaction rates. The compound's reactivity is influenced by steric and electronic factors, allowing for tailored modifications in synthetic routes. Additionally, its solubility properties enhance its compatibility with various solvents, facilitating diverse chemical transformations.

Desmethyl doxylamine-d5

1221-70-1 (unlabeled)sc-500285
2.5 mg
$380.00
(0)

Desmethyl doxylamine-d5 exhibits distinctive reactivity as an acid halide, primarily through its capacity for rapid electrophilic attack on nucleophiles. The presence of deuterium isotopes enhances its kinetic stability, allowing for precise tracking in mechanistic studies. Its unique steric configuration influences the selectivity of acylation reactions, while its polar characteristics improve solvation dynamics, enabling efficient participation in complex synthetic pathways.

N-Demethyl N-acetyl alogliptin-2,2,2-trifluoroacetate

sc-500411
5 mg
$430.00
(0)

N-Demethyl N-acetyl alogliptin-2,2,2-trifluoroacetate demonstrates remarkable reactivity as an acid halide, characterized by its ability to form stable intermediates during nucleophilic acyl substitution. The trifluoroacetate moiety imparts significant electron-withdrawing effects, enhancing electrophilicity and facilitating rapid reaction kinetics. Its unique spatial arrangement promotes selective interactions with various nucleophiles, while its solubility properties allow for effective integration into diverse chemical environments.

GI 254023X

260264-93-5sc-490114
1 mg
$163.00
1
(0)

This compound is a potent and selective inhibitor of ADAM17 and has been explored for its role in modulating the

Carfilzomib

868540-17-4sc-396755
5 mg
$40.00
(0)

Originally developed as a proteasome inhibitor, PR-171 has also been found to inhibit A Disintegrin And Metalloproteinases and reduce its enzymatic activity.

SB-3CT

292605-14-2sc-205847
sc-205847A
1 mg
5 mg
$100.00
$380.00
15
(1)

Originally developed as a matrix metalloproteinase inhibitor, SB-3CT has been found to inhibit A Disintegrin And Metalloproteinases and reduce its enzymatic activity.

NNGH

161314-17-6sc-222075
5 mg
$95.00
2
(1)

An inhibitor of ADAMs, including A Disintegrin And Metalloproteinases, that has been used to study metalloproteinase functions.