Date published: 2026-1-12

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Activin Activators

Activin is a complex protein that plays a vital role in many biological processes. It belongs to the transforming growth factor-beta (TGF-β) superfamily, a group of proteins known for their extensive involvement in cellular functions such as cell growth, differentiation, and apoptosis. Predominantly recognized for its function in embryogenesis and tissue repair in adults, Activin is a dimeric protein, usually composed of two identical or very similar beta subunits, often referred to as inhibin beta. This protein is implicated in a variety of important biological functions including metabolism, homeostasis, immune response, wound healing, and endocrine function. Its expression can be responsive to numerous stimuli, providing a dynamic and adaptive component to cellular and organismal physiology.

The expression of Activin can be influenced by various chemical compounds, each having the potential to interact with cellular systems in a unique way to promote its production. For instance, Retinoic Acid and Vitamin D3 are known to interact with nuclear receptors, instigating a chain of events that can enhance the expression of Activin. Similarly, hormones like Estradiol, Progesterone, and Testosterone can bind to their respective receptors and may stimulate the transcription of Activin. Certain compounds like Dexamethasone and Insulin can also bind to their specific receptors, initiating a signaling cascade that may lead to an increase in Activin expression. Additionally, compounds like Forskolin, Lithium Chloride, Sodium Butyrate, Epigallocatechin Gallate (EGCG), and Resveratrol have been shown to alter various cellular processes and pathways and may promote the expression of Activin. Each of these compounds illustrates the diverse array of chemical activators that can potentially induce the expression of this multifunctional protein.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid serves as a ligand for nuclear receptors, stimulating a cascade of events that can upregulate the expression of activin.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 (Cholecalciferol), through its active metabolite Calcitriol, can enhance the transcription of genes like activin, by binding to the vitamin D response elements (VDREs) in their promoter regions.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

β-Estradiol can bind to the estrogen receptor, triggering a series of events that promote the transcription and subsequent expression of certain genes, possibly including activin.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$52.00
$298.00
3
(1)

Progesterone can bind to progesterone receptors, triggering a chain of events that may stimulate the transcription and subsequent expression of genes, including activin.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a synthetic glucocorticoid, can bind to glucocorticoid receptors, initiating a cascade of events that may enhance the transcription and subsequent elevated expression of genes, such as activin.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin, by activating the insulin receptor, can trigger a signaling cascade that may stimulate the transcription of certain genes, including activin, leading to their increased expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin, by increasing intracellular cyclic AMP levels, may stimulate a series of cellular events leading to the enhanced transcription and subsequent expression of genes, potentially including activin.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride can inhibit the activity of glycogen synthase kinase-3 beta (GSK-3β), which may lead to an altered transcription landscape, possibly promoting the expression of activin.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate, a short-chain fatty acid, can inhibit histone deacetylases, altering chromatin structure and potentially promoting the transcription and subsequent expression of genes, such as activin.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Epigallocatechin Gallate, a polyphenol found in green tea, can inhibit certain kinases and other proteins, potentially leading to the increased transcription and subsequent expression of genes, like activin.