Date published: 2025-9-17

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 371 to 374 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-(3-Fluoro-phenyl)-ethanesulfonyl chloride

728919-65-1sc-320582
1 g
$745.00
(0)

2-(3-Fluoro-phenyl)-ethanesulfonyl chloride is a distinctive acid halide featuring a sulfonyl chloride moiety that imparts significant electrophilicity. The fluorine substituent enhances the compound's reactivity by stabilizing negative charges through inductive effects, facilitating nucleophilic attack. This compound exhibits unique solubility characteristics, promoting rapid reaction rates in polar solvents. Its ability to form sulfonamide derivatives underscores its utility in diverse synthetic strategies, particularly in functional group transformations.

2-Bromo-1-cyclopropyl-2-(3-fluorophenyl)ethanone

1359829-72-3sc-504032
100 mg
$380.00
(0)

2-Bromo-1-cyclopropyl-2-(3-fluorophenyl)ethanone stands out as a reactive acid halide, exhibiting pronounced electrophilic characteristics due to its unique cyclopropyl and fluorophenyl substituents. These groups enhance its reactivity, allowing for rapid nucleophilic substitution reactions. The compound's steric and electronic properties influence its interaction with nucleophiles, leading to varied reaction pathways and kinetics. Its ability to stabilize transition states makes it a key player in complex organic transformations.

2-Bromo-1-cyclopropyl-2-(4-fluorophenyl)ethanone

1359829-52-9sc-504034
50 mg
$393.00
(0)

2-Bromo-1-cyclopropyl-2-(4-fluorophenyl)ethanone is a distinctive acid halide characterized by its potent electrophilic nature, driven by the interplay of its bromine and fluorine substituents. The presence of the cyclopropyl ring introduces unique steric effects, facilitating selective nucleophilic attacks. This compound's reactivity is further modulated by the electron-withdrawing fluorine, which enhances its susceptibility to hydrolysis and other nucleophilic additions, making it a versatile intermediate in synthetic pathways.

2-Bromo-1-cyclopropyl-2-phenylethanone

34650-68-5sc-504035
500 mg
$380.00
(0)

2-Bromo-1-cyclopropyl-2-phenylethanone exhibits remarkable reactivity as an acid halide, primarily due to its electrophilic carbonyl group, which is significantly influenced by the adjacent bromine atom. The cyclopropyl moiety introduces unique strain, promoting rapid reaction kinetics with nucleophiles. Additionally, the compound's ability to undergo acylation reactions is enhanced by the presence of the phenyl group, allowing for diverse synthetic applications and facilitating complex molecular transformations.