Date published: 2025-9-28

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 171 to 180 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-(chlorosulfonyl)phenyl 4-methylbenzenesulfonate

sc-348295
sc-348295A
250 mg
1 g
$197.00
$399.00
(0)

4-(Chlorosulfonyl)phenyl 4-methylbenzenesulfonate, as an acid halide, exhibits remarkable reactivity due to its dual sulfonate functionalities. The chlorosulfonyl moiety enhances electrophilicity, facilitating rapid nucleophilic substitution reactions. Its sterically hindered structure influences reaction kinetics, often leading to regioselective outcomes. Additionally, the compound's ability to engage in both intermolecular and intramolecular interactions can stabilize reactive intermediates, guiding synthetic pathways effectively.

5-fluoro-2-nitrobenzene-1-sulfonyl chloride

sc-350987
sc-350987A
250 mg
1 g
$288.00
$584.00
(0)

5-Fluoro-2-nitrobenzene-1-sulfonyl chloride, as an acid halide, showcases unique reactivity stemming from its electron-withdrawing nitro group, which significantly enhances electrophilic character. This compound readily participates in acylation reactions, where its sulfonyl chloride functionality acts as a potent electrophile. The presence of the fluorine atom introduces distinct steric and electronic effects, influencing reaction selectivity and kinetics, while promoting diverse synthetic routes through effective leaving group behavior.

Iminostilbene N-Carbonyl Chloride

33948-22-0sc-211636
5 g
$173.00
(0)

Iminostilbene N-Carbonyl Chloride, as an acid halide, exhibits remarkable reactivity due to its carbonyl group, which enhances its electrophilic nature. This compound readily engages in nucleophilic acyl substitution, facilitating the formation of amides and esters. Its unique structural features allow for selective reactions with various nucleophiles, while the presence of the imino group can influence steric hindrance and reaction rates, leading to diverse synthetic pathways.

2-Thiazolesulfonyl Chloride

100481-09-2sc-206491
50 mg
$400.00
(0)

2-Thiazolesulfonyl Chloride, functioning as an acid halide, showcases distinctive reactivity attributed to its thiazole ring and sulfonyl group. This compound is highly electrophilic, promoting rapid nucleophilic attack and subsequent acyl substitution reactions. The presence of the sulfonyl moiety enhances its ability to stabilize intermediates, influencing reaction kinetics. Its unique structure allows for selective interactions with a range of nucleophiles, enabling versatile synthetic applications.

Palmitoyl chloride

112-67-4sc-281122
sc-281122A
100 ml
500 ml
$107.00
$495.00
(0)

Palmitoyl chloride, as an acid halide, exhibits remarkable reactivity due to its long-chain fatty acyl structure. This compound is characterized by its strong electrophilic nature, facilitating swift acylation reactions with nucleophiles. The hydrophobic tail enhances its solubility in organic solvents, promoting efficient reaction pathways. Additionally, its ability to form stable acyl intermediates allows for controlled reaction kinetics, making it a key player in various synthetic transformations.

3-carbamoylbenzene-1-sulfonyl chloride

sc-346609
sc-346609A
1 g
5 g
$584.00
$1725.00
(0)

3-Carbamoylbenzene-1-sulfonyl chloride, as an acid halide, showcases a unique combination of sulfonyl and carbamoyl functionalities, enhancing its electrophilicity. This compound readily engages in nucleophilic acyl substitution, leading to the formation of diverse sulfonamide derivatives. Its polar sulfonyl group increases solubility in polar solvents, while the aromatic ring stabilizes transition states, influencing reaction rates and selectivity in synthetic pathways.

2-(2-oxoquinoxalin-1(2H)-yl)ethanesulfonyl fluoride

877977-29-2sc-339561
sc-339561A
250 mg
1 g
$240.00
$490.00
(0)

2-(2-oxoquinoxalin-1(2H)-yl)ethanesulfonyl fluoride, functioning as an acid halide, exhibits remarkable reactivity due to its unique quinoxaline structure, which facilitates strong π-stacking interactions. This compound is prone to nucleophilic attack, resulting in the formation of sulfonyl derivatives. Its fluorine substituent enhances electrophilic character, promoting rapid reaction kinetics. Additionally, the compound's polar nature contributes to its solubility in various solvents, influencing its behavior in synthetic applications.

3-Methylfuran-2-carbonyl chloride

22601-06-5sc-226156
1 g
$69.00
(0)

3-Methylfuran-2-carbonyl chloride, as an acid halide, showcases distinctive reactivity stemming from its furan ring, which enhances electrophilicity through resonance effects. This compound readily undergoes acylation reactions, making it a versatile intermediate in organic synthesis. Its ability to form stable adducts with nucleophiles is influenced by the electron-withdrawing carbonyl group, while the chloride moiety facilitates rapid substitution reactions, leading to diverse synthetic pathways.

Propionyl chloride

79-03-8sc-236483
sc-236483A
25 g
500 g
$62.00
$112.00
(0)

Propionyl chloride, an acid halide, exhibits notable reactivity due to its carbonyl and halogen functionalities. The presence of the carbonyl group enhances its electrophilic character, allowing for efficient acylation with various nucleophiles. Its reactivity is further amplified by the chloride, which promotes swift nucleophilic substitution. This compound can also participate in condensation reactions, forming an array of derivatives, thus serving as a key building block in synthetic chemistry.

(2-fluorophenyl)methanesulfonyl chloride

24974-71-8sc-342738
sc-342738A
1 g
5 g
$140.00
$500.00
(0)

(2-fluorophenyl)methanesulfonyl chloride, as an acid halide, showcases unique reactivity stemming from its sulfonyl and halogen components. The sulfonyl group enhances electrophilicity, facilitating rapid reactions with nucleophiles. Its fluorinated aromatic ring can influence electronic distribution, potentially altering reaction pathways and selectivity. This compound is also prone to hydrolysis, leading to the formation of sulfonic acids, which can further engage in diverse chemical transformations.