Date published: 2025-10-1

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 91 to 100 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3,4-Dimethoxybenzoyl chloride

3535-37-3sc-238655
5 g
$62.00
(0)

3,4-Dimethoxybenzoyl chloride is a notable acid halide characterized by its methoxy substituents, which significantly influence its electronic properties and sterics. The electron-donating nature of the methoxy groups enhances the electrophilicity of the carbonyl carbon, promoting efficient nucleophilic acyl substitution. This compound exhibits unique reactivity patterns, allowing for selective functionalization in complex organic syntheses, while its aromatic structure contributes to stability and resonance effects during reactions.

2,6-Dichlorobenzoyl chloride

4659-45-4sc-238402
10 g
$53.00
(0)

2,6-Dichlorobenzoyl chloride is a distinctive acid halide featuring two chlorine substituents that enhance its reactivity through strong electron-withdrawing effects. This configuration increases the electrophilic character of the carbonyl carbon, facilitating rapid nucleophilic attack. The presence of chlorine atoms also introduces steric hindrance, influencing reaction pathways and selectivity. Its aromatic framework provides resonance stabilization, allowing for diverse synthetic applications and unique interaction dynamics in various chemical environments.

4-Methoxyphenylacetyl chloride

4693-91-8sc-238891
2 g
$35.00
(0)

4-Methoxyphenylacetyl chloride is an acid halide distinguished by its methoxy-substituted aromatic ring, which enhances its electrophilic character. The methoxy group not only increases the electron density on the aromatic system but also influences the sterics of nucleophilic attack, leading to selective reactivity. Its carbonyl chloride moiety facilitates swift acylation reactions, while the aromatic resonance stabilizes intermediates, allowing for versatile synthetic pathways in organic chemistry.

2-(2,5-dimethylphenyl)-6-methylquinoline-4-carbonyl chloride

sc-320533
100 mg
$150.00
(0)

2-(2,5-dimethylphenyl)-6-methylquinoline-4-carbonyl chloride is a notable acid halide characterized by its quinoline structure, which imparts unique electronic properties. The presence of the dimethylphenyl group enhances steric effects, influencing the reactivity and selectivity in nucleophilic acyl substitution reactions. Its carbonyl chloride functionality exhibits high electrophilicity, promoting rapid reaction kinetics. Additionally, the aromatic system contributes to resonance stabilization, allowing for diverse reactivity patterns in synthetic chemistry.

3-Isocyanatobenzoyl chloride

5180-79-0sc-231778
1 g
$37.00
(0)

3-Isocyanatobenzoyl chloride is an acid halide characterized by its isocyanate functional group, which imparts unique reactivity patterns. This compound exhibits strong electrophilic behavior, enabling rapid acylation and nucleophilic substitution reactions. The presence of the isocyanate enhances the potential for forming stable urea derivatives, while its aromatic structure contributes to resonance stabilization of reaction intermediates. This interplay of functionalities allows for diverse synthetic applications in organic chemistry.

3,3-Dimethylbutyryl chloride

7065-46-5sc-238636
25 g
$78.00
(0)

3,3-Dimethylbutyryl chloride is an acid halide notable for its sterically hindered structure, which influences its reactivity and selectivity in nucleophilic acyl substitution reactions. The bulky dimethyl groups create a unique steric environment, leading to slower reaction kinetics compared to less hindered acid chlorides. This compound's electrophilic carbonyl carbon is highly reactive, facilitating the formation of acyl derivatives while minimizing side reactions, making it a versatile intermediate in organic synthesis.

2,3-Dichloropropionyl chloride

7623-13-4sc-238275
1 g
$210.00
(0)

2,3-Dichloropropionyl chloride is an acid halide characterized by its unique dichlorinated structure, which enhances its electrophilicity and reactivity in acylation reactions. The presence of two chlorine atoms adjacent to the carbonyl group increases the electron-withdrawing effect, promoting rapid nucleophilic attack. This compound exhibits distinct reactivity patterns, often leading to selective acylation pathways and the formation of diverse acyl derivatives, making it a significant intermediate in synthetic chemistry.

3-Methoxybenzenesulfonyl chloride

10130-74-2sc-226116
1 g
$90.00
(0)

3-Methoxybenzenesulfonyl chloride is an acid halide distinguished by its sulfonyl chloride functionality, which imparts unique reactivity in nucleophilic substitution reactions. The methoxy group enhances electron density on the aromatic ring, facilitating electrophilic aromatic substitution. This compound exhibits rapid reaction kinetics, often leading to the formation of sulfonamides and other derivatives. Its ability to engage in diverse coupling reactions makes it a versatile building block in organic synthesis.

(3,4-Dimethoxyphenyl)acetyl chloride

10313-60-7sc-223563
sc-223563A
5 g
25 g
$97.00
$368.00
(0)

(3,4-Dimethoxyphenyl)acetyl chloride is an acid halide characterized by its acetyl chloride moiety, which enhances its reactivity towards nucleophiles. The presence of two methoxy groups on the aromatic ring increases electron density, promoting electrophilic interactions. This compound readily participates in acylation reactions, leading to the formation of esters and amides. Its unique steric and electronic properties allow for selective reactivity, making it a useful intermediate in various synthetic pathways.

4-Methyl-3-nitrobenzoyl chloride

10397-30-5sc-254703
10 ml
$46.00
(0)

4-Methyl-3-nitrobenzoyl chloride is a reactive acid halide characterized by its electrophilic carbonyl group, which facilitates nucleophilic acyl substitution reactions. The presence of the nitro group enhances its reactivity by stabilizing the transition state, leading to faster reaction kinetics. This compound can engage in diverse coupling reactions, forming esters and amides, and exhibits distinct solubility properties due to its polar functional groups, influencing its behavior in various organic syntheses.