Date published: 2025-10-16

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Acetylation

Santa Cruz Biotechnology now offers a broad range of acetylation reagents for use in various applications. Acetylation, a chemical reaction involving the introduction of an acetyl group into a molecule, is a crucial process in scientific research due to its significant role in modifying proteins, nucleic acids, and other biomolecules. This modification can alter the function, stability, and interaction of proteins, thereby influencing cellular processes such as gene expression, signal transduction, and metabolism. Researchers use acetylation to study epigenetic regulation, where acetylation of histones plays a key role in chromatin structure and gene accessibility. In molecular biology, acetylation reagents are essential for investigating protein-protein interactions and post-translational modifications, providing insights into cellular mechanisms and disease states. In the field of biochemistry, acetylation is used to modify small molecules and develop inhibitors or activators of specific enzymes, facilitating drug discovery and the development of biochemical assays. Additionally, acetylation is employed in the synthesis of various chemicals, including agrochemicals, and polymers, showcasing its versatility in chemical engineering. Environmental scientists utilize acetylation techniques to analyze pollutants and study their impact on ecosystems. The broad applicability and fundamental importance of acetylation reagents in diverse scientific disciplines underscore their critical role in advancing research and technological innovation. View detailed information on our available acetylation reagents by clicking on the product name.

Items 51 to 60 of 80 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

TC-H 106

937039-45-7sc-362801
sc-362801A
10 mg
50 mg
$155.00
$620.00
(0)

TC-H 106 serves as a potent acetylation reagent, notable for its rapid reaction kinetics and selective reactivity towards nucleophiles. Its unique structure promotes effective orbital overlap, enhancing electrophilic character and facilitating acyl transfer. The compound's reactivity is influenced by steric hindrance, allowing for tailored substrate interactions. Furthermore, TC-H 106 demonstrates resilience in diverse conditions, ensuring consistent performance in acylation processes.

4-iodo-SAHA

1219807-87-0sc-364391
sc-364391A
50 mg
250 mg
$147.00
$663.00
(0)

4-Iodo-SAHA is a highly reactive acetylation agent characterized by its ability to engage in rapid electrophilic acyl transfer. The presence of the iodine atom enhances its electrophilicity, promoting efficient interactions with nucleophiles. Its unique steric profile allows for selective targeting of specific functional groups, while its stability under varying conditions ensures reliable performance in diverse chemical environments. This compound's distinct reactivity patterns make it a versatile tool in synthetic chemistry.

KD 5170

940943-37-3sc-362755
10 mg
$398.00
(0)

KD 5170 is a potent acetylation reagent known for its exceptional reactivity due to its acid halide nature. It facilitates acylation through a mechanism that involves the formation of a highly reactive acylium ion, which readily interacts with nucleophiles. The compound exhibits unique selectivity, allowing for the modification of specific functional groups while minimizing side reactions. Its kinetic profile showcases rapid reaction rates, making it an efficient choice for various synthetic applications.

MC 1293

sc-221875
5 mg
$202.00
1
(0)

MC 1293 is a highly reactive acetylation agent characterized by its ability to form stable intermediates during acylation reactions. As an acid halide, it engages in nucleophilic attack, leading to the generation of acyloxy species that enhance selectivity for target substrates. The compound's unique steric and electronic properties influence its reactivity, allowing for controlled modifications of complex molecules. Its rapid kinetics enable efficient transformations, making it a versatile tool in synthetic chemistry.

Acetyl chloride

75-36-5sc-207253
sc-207253A
25 g
500 g
$30.00
$50.00
(0)

Acetyl chloride is a potent acetylation reagent known for its vigorous reactivity with nucleophiles, facilitating the formation of acyl derivatives. Its electrophilic nature promotes swift acyl transfer, often resulting in the generation of reactive intermediates that can undergo further transformations. The compound's polar nature enhances solubility in organic solvents, while its ability to form stable complexes with amines and alcohols allows for selective modifications in diverse synthetic pathways.

Indole-3-acetamide

879-37-8sc-255213
sc-255213A
1 g
5 g
$44.00
$198.00
1
(0)

Indole-3-acetamide exhibits unique reactivity as an acetylation agent, characterized by its ability to engage in selective acylation reactions with various nucleophiles. The presence of the indole moiety enhances its electrophilic character, allowing for efficient acyl transfer. Its distinct steric and electronic properties facilitate specific interactions with substrates, leading to diverse reaction pathways. Additionally, the compound's solubility in organic solvents supports its utility in complex synthetic schemes.

Bufexamac

2438-72-4sc-227537
10 g
$75.00
(0)

Bufexamac demonstrates intriguing behavior as an acetylation agent, primarily due to its unique structural features that influence reactivity. The compound's ability to form stable intermediates during acylation reactions is notable, as it allows for controlled reaction kinetics. Its polar functional groups enhance solvation effects, promoting effective interactions with nucleophiles. Furthermore, Bufexamac's distinct steric hindrance can direct regioselectivity, leading to varied product distributions in synthetic applications.

1-Acetylimidazole

2466-76-4sc-253880
25 g
$39.00
(0)

1-Acetylimidazole serves as a versatile acetylation agent, characterized by its ability to engage in rapid acyl transfer reactions. The presence of the imidazole ring facilitates strong hydrogen bonding interactions, enhancing its reactivity with nucleophiles. This compound exhibits unique electrophilic properties, allowing for selective acetylation of various substrates. Additionally, its moderate polarity aids in solubility, promoting efficient reaction conditions and diverse synthetic pathways.

NSC 3852

3565-26-2sc-205773
sc-205773A
10 mg
50 mg
$102.00
$173.00
(1)

NSC 3852 is a potent acetylation reagent known for its unique reactivity profile as an acid halide. Its electrophilic carbonyl carbon is highly susceptible to nucleophilic attack, enabling swift acylation of alcohols and amines. The compound's steric properties influence reaction kinetics, allowing for selective modifications in complex substrates. Furthermore, its ability to form stable intermediates enhances the efficiency of synthetic routes, making it a valuable tool in organic synthesis.

Trichostatin C

68676-88-0sc-202369
500 µg
$359.00
2
(1)

Trichostatin C is a notable acetylation agent characterized by its ability to modulate histone acetylation through specific interactions with lysine residues. This compound exhibits a unique mechanism of action, facilitating the transfer of acetyl groups via a reversible binding process. Its structural features allow for selective targeting of histone deacetylases, influencing gene expression pathways. The compound's reactivity is enhanced by its conformational flexibility, promoting efficient acetylation in diverse biological contexts.