Date published: 2025-10-20

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ACC Inhibitors

Santa Cruz Biotechnology now offers a broad range of ACC Inhibitors for use in various applications. ACC inhibitors are specialized compounds that target acetyl-CoA carboxylase (ACC), a key enzyme involved in fatty acid biosynthesis. ACC catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which is a crucial step in the synthesis of long-chain fatty acids. This enzyme plays a significant role in regulating lipid metabolism, making ACC inhibitors vital tools for scientific research. Researchers use ACC inhibitors to study the mechanisms of lipid synthesis and breakdown, exploring how changes in ACC activity affect cellular energy balance, lipid storage, and metabolic homeostasis. These inhibitors are also employed to investigate the role of ACC in various physiological processes, such as insulin signaling, adipogenesis, and the development of metabolic diseases. By blocking ACC activity, scientists can dissect the pathways involved in fatty acid metabolism and gain insights into the regulation of lipid-related cellular functions. The high-purity ACC inhibitors provided by Santa Cruz Biotechnology ensure that experiments are conducted with precision and reproducibility, yielding reliable data essential for advancing our understanding of metabolic regulation. These inhibitors support the scientific community in developing new experimental models and uncovering novel insights into the control of lipid metabolism and its implications for health and disease. View detailed information on our available ACC Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

TOFA (5-(Tetradecyloxy)-2-furoic acid)

54857-86-2sc-200653
sc-200653A
10 mg
50 mg
$95.00
$367.00
15
(1)

TOFA, as an ACC, exhibits distinctive molecular interactions that facilitate its role in metabolic pathways. Its long hydrophobic tail enhances membrane affinity, promoting effective integration into lipid bilayers. This structural characteristic allows for unique interactions with lipid enzymes, potentially influencing their activity. Additionally, TOFA's furoic acid moiety can engage in specific ionic interactions, modulating the reactivity and stability of associated biochemical systems.

MEDICA 16

87272-20-6sc-203131
sc-203131A
5 mg
10 mg
$188.00
$260.00
1
(1)

MEDICA 16, functioning as an acid chloride, showcases remarkable reactivity due to its electrophilic carbonyl group, which readily engages in nucleophilic acyl substitution reactions. Its unique structure allows for rapid acylation of amines and alcohols, leading to the formation of stable amides and esters. The presence of halogen atoms enhances its reactivity, facilitating diverse synthetic pathways and enabling selective modifications in complex organic frameworks.