Chemicals classified as Teddm2 Inhibitors are not specific to the Teddm2 protein but are thought to act through indirect modulation of various signaling pathways that could impact the function of Teddm2. These compounds affect different kinases and signaling molecules, which are integral to numerous cellular processes. For instance, Genistein and Staurosporine are inhibitors that target tyrosine kinases and protein kinases broadly, respectively, and can alter the phosphorylation status of a wide array of proteins, potentially including Teddm2 if it is phosphorylated as part of its regulation.
Compounds like LY294002, PP2, and PD173074 inhibit specific kinase activities, such as PI3K, Src family kinases, and FGFR tyrosine kinase. These enzymes are part of signaling cascades that regulate cell growth, survival, and differentiation. Inhibitors such as SB431542 and U73122 interfere with TGF-beta signaling and phospholipase C activity, respectively, which are important for cellular communication and response to external stimuli. KN-93, Y-27632, PD98059, and Gö 6983 target CaMKII, ROCK kinase, MEK, and protein kinase C isoforms, respectively, each affecting cellular signaling in a different manner.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Inhibits tyrosine kinases, possibly affecting signaling pathways that regulate proteins like Teddm2. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Inhibits a broad range of protein kinases, potentially altering signaling cascades that affect Teddm2. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Inhibits protein kinase C, which can modulate signaling pathways influencing Teddm2. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Inhibits Src family kinases, which can affect signaling pathways potentially connected to Teddm2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, potentially affecting signaling pathways that Teddm2 may be a part of. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
Inhibits FGFR tyrosine kinase, which can affect signaling pathways that regulate Teddm2. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
Inhibits TGF-beta receptor kinase, potentially affecting pathways that Teddm2 may be involved in. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibits CaMKII, which can modulate signaling pathways that may influence Teddm2. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK kinase, potentially affecting pathways that regulate Teddm2's function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which may affect MAPK pathway activity and thus influence Teddm2 function. | ||||||