Date published: 2026-1-9

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53BP1 Antibodies

Santa Cruz Biotechnology provides a broad selection of 53BP1 monoclonal antibodies for various research applications. 53BP1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). 53BP1, or p53-binding protein 1, plays a critical role in the DNA damage response and is essential for maintaining genomic stability. The protein actively participates in DNA repair processes, particularly during double-strand breaks, and demonstrates significant tumor suppression capabilities. Understanding 53BP1 function has revealed important insights into cellular responses to DNA damage and the development of various diseases. Research focusing on 53BP1 continues to advance our knowledge of DNA repair mechanisms and their impact on human health. Investigating 53BP1's role in tumor suppression has opened new avenues for cancer research and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of DNA damage response pathways and their implications in disease development.

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53BP1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

53BP1 Antibody (E-10)

sc-515841mouse IgG1 λ1221-1239 (m)WB, IP, IF, ELISAm, r, h
17
(13)

53BP1 Antibody (6B3E10)

sc-517281mouse IgG1574-773 (h)WB, IP, IF, IHC(P), FCM, ELISAh
9
(1)

Phospho-Specific 53BP1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-53BP1 Antibody (38.Ser 25)

sc-135748mouse IgG1 κSer 25 (m)WB, IP, ELISAm, h
1
(3)

53BP1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

53BP1 CRISPR/Cas9 KO Plasmid (h2)

sc-400321-KO-2hGene KnockoutGFP0
(0)

53BP1 HDR Plasmid (h2)

sc-400321-HDR-2hHomology Directed RepairPuromycin0
(0)

53BP1 Double Nickase Plasmid (h)

sc-400321-NIChGene KnockoutPuromycin0
(0)

53BP1 Double Nickase Plasmid (h2)

sc-400321-NIC-2hGene KnockoutPuromycin0
(0)

53BP1 CRISPR/Cas9 KO Plasmid (m2)

sc-424212-KO-2mGene KnockoutGFP0
(1)

53BP1 Double Nickase Plasmid (m)

sc-424212-NICmGene KnockoutPuromycin0
(1)

53BP1 Double Nickase Plasmid (m2)

sc-424212-NIC-2mGene KnockoutPuromycin0
(1)

53BP1 CRISPR Activation Products

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53BP1 CRISPR Activation Plasmid (h)

sc-400321-ACThGene ActivationPuro, Blast, Hygro0
(0)

53BP1 CRISPR Activation Plasmid (h2)

sc-400321-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

53BP1 Lentiviral Activation Particles (h)

sc-400321-LAChGene ActivationPuro, Blast, Hygro0
(0)

53BP1 Lentiviral Activation Particles (h2)

sc-400321-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

53BP1 CRISPR Activation Plasmid (m)

sc-424212-ACTmGene ActivationPuro, Blast, Hygro0
(1)

53BP1 CRISPR Activation Plasmid (m2)

sc-424212-ACT-2mGene ActivationPuro, Blast, Hygro0
(1)

53BP1 Lentiviral Activation Particles (m)

sc-424212-LACmGene ActivationPuro, Blast, Hygro0
(1)

53BP1 Lentiviral Activation Particles (m2)

sc-424212-LAC-2mGene ActivationPuro, Blast, Hygro0
(1)

53BP1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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53BP1 siRNA (h)

sc-37455hGene SilencingN/A
3
(0)

53BP1 shRNA Plasmid (h)

sc-37455-SHhGene SilencingPuromycin
3
(0)

53BP1 shRNA (h) Lentiviral Particles

sc-37455-VhGene SilencingPuromycin
3
(0)

53BP1 siRNA (m)

sc-37456mGene SilencingN/A0
(0)

53BP1 shRNA Plasmid (m)

sc-37456-SHmGene SilencingPuromycin0
(0)

53BP1 shRNA (m) Lentiviral Particles

sc-37456-VmGene SilencingPuromycin0
(0)