4933427G17Rik Inhibitors

Mfsd13b Inhibitors are a group of compounds that can indirectly modulate the function of the Mfsd13b protein. These inhibitors do not interact with Mfsd13b directly but influence the cellular pathways and processes that Mfsd13b may be involved in. For example, compounds such as glucose and phlorizin can interact with the substrate transport function of Mfsd13b. High concentrations of glucose can lead to the down-regulation of Mfsd13b expression or activity, while phlorizin can alter substrate availability for Mfsd13b by competitively inhibiting similar transporters.

Other compounds, such as nitrendipine and verapamil, can affect the protein indirectly through modulation of calcium homeostasis or by inhibiting drug transport processes that Mfsd13b might participate in. Curcumin and quercetin can influence the protein due to their effects on transport proteins, possibly altering Mfsd13b's activity if it has overlapping substrate specificities. Cyclosporin A and reserpine are examples of compounds that can affect Mfsd13b by their action on multidrug resistance proteins or on vesicular storage mechanisms, respectively. Progesterone represents a hormonal regulation pathway that can affect the expression and activity of Mfsd13b.