4932418E24Rik Inhibitors
Compounds classified as CCDC187 Inhibitors are not direct inhibitors of the CCDC187 protein but can influence cellular processes and structures where CCDC187 may play a role. These chemical agents target various aspects of cytoskeletal dynamics and cell division, pathways in which CCDC187 could be implicated. For example, molecules like paclitaxel, nocodazole, vinblastine, and colchicine act on the microtubule network, a key component of the cytoskeleton and cell division machinery, by either stabilizing or destabilizing microtubules. This can lead to disrupted cell division and may affect the function of proteins like CCDC187, which could be involved in these processes.
Additionally, cytochalasin D, latrunculin A, swinholide A, and jasplakinolide target actin filaments, a major component of the cytoskeleton, by inhibiting polymerization or severing filaments. This can alter the overall architecture of the cell and potentially interfere with any role that CCDC187 might have in maintaining cellular structure. Inhibitors like blebbistatin, Y-27632, ML-7, and withaferin A disrupt the function of myosin and related kinases, which are crucial for cellular contractility and stability.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules; can disrupt cell division, possibly affecting CCDC187's role in this process. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Microtubule polymerization inhibitor; can disrupt microtubule dynamics, possibly influencing CCDC187 function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Microtubule destabilizer; can perturb mitotic spindle formation, possibly affecting CCDC187-related processes. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds tubulin, preventing polymerization; can interfere with microtubule function, potentially impacting CCDC187. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin polymerization; can affect cytoskeletal organization, possibly influencing CCDC187's role. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Binds monomeric G-actin, inhibiting actin polymerization; can disrupt actin dynamics, potentially affecting CCDC187. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II; can disrupt cytoskeletal tension and cellular contractility, potentially affecting CCDC187's function. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor; can reduce actomyosin contractility, possibly influencing CCDC187's role in cellular architecture. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Myosin light chain kinase inhibitor; can alter cytoskeletal dynamics, potentially impacting CCDC187. | ||||||
Swinholide A, Theonella swinhoei | 95927-67-6 | sc-205914 | 10 µg | $135.00 | ||
Actin filament severing and capping protein; can disrupt actin cytoskeleton, potentially affecting CCDC187's role. | ||||||