Date published: 2025-10-10

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2410012M07Rik Inhibitors

Chemicals classified as PRR23A3 Inhibitors are not directly inhibiting PRR23A3 but can influence the biological processes and signaling pathways that might intersect with the functional landscape of PRR23A3. Given the role of protein kinases in signal transduction and regulation of a myriad of cellular processes, inhibitors like Genistein, LY294002, and PD98059 can modify the activity of various kinases, thereby altering signaling pathways that PRR23A3 may be part of. These changes in kinase activity can lead to modified transcriptional programs and cellular responses, potentially impacting the function of PRR23A3.

Further, the intricacies of cell signaling involve multiple layers of regulation. Compounds such as Rapamycin and Y-27632 target key components of growth and cytoskeletal organization pathways, respectively, which are fundamental to cell function and behavior. By altering these pathways, the chemicals can indirectly influence the functional context within which PRR23A3 operates. Additionally, pathway-specific inhibitors like IWP-2, DAPT, Cyclopamine, and XAV939 target the production or activity of signaling molecules within the Wnt, Notch, and Hedgehog pathways, respectively.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Inhibits tyrosine kinases and can alter cellular signaling pathways, potentially affecting PRR23A3.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Inhibits PI3K, which is involved in a variety of signaling pathways, potentially affecting PRR23A3.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Inhibits MEK, which can alter the MAPK/ERK pathway, potentially affecting PRR23A3.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which can alter AP-1 transcription factor activity, potentially affecting PRR23A3.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

Inhibits p38 MAPK, potentially affecting stress response pathways linked to PRR23A3.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Inhibits MEK1/2, potentially affecting the MAPK/ERK pathway and thereby influencing PRR23A3.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Inhibits mTOR, which can affect cell growth and proliferation pathways involving PRR23A3.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Inhibits ROCK, potentially affecting cytoskeletal organization and related processes involving PRR23A3.

IWP-2

686770-61-6sc-252928
sc-252928A
5 mg
25 mg
$94.00
$286.00
27
(1)

Inhibits Wnt production, potentially affecting Wnt signaling pathways involving PRR23A3.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$99.00
$335.00
$836.00
$2099.00
47
(3)

Inhibits gamma-secretase, potentially affecting Notch signaling pathways involving PRR23A3.