1700113I22Rik Inhibitors
1700113I22Rik inhibitors refers to a class of chemical compounds specifically designed or discovered to modulate the activity or function of the protein coded by the gene 1700113I22Rik. These inhibitors are essential tools in the field of molecular biology and cellular research, where they play a critical role in elucidating the biological functions and regulatory mechanisms associated with this particular protein. Inhibitors within this class may vary widely in terms of their chemical structure, mechanism of action, and specificity for the target protein, depending on the specific research objectives and experimental requirements.
These inhibitors are typically employed to perturb the normal function of the 1700113I22Rik protein in a controlled and reversible manner. Researchers use them to gain insights into the protein's role within cellular pathways, signaling cascades, or biochemical processes. By inhibiting 1700113I22Rik, researchers can investigate how its absence or altered function affects cellular functions and responses. This approach helps uncover the physiological and pathological relevance of 1700113I22Rik, providing valuable knowledge about its involvement in various cellular processes. Researchers often conduct experiments using these inhibitors in cell culture or animal models to observe changes in cellular behavior, gene expression, or downstream signaling events. The outcomes of such studies can contribute to a deeper understanding of the specific functions and molecular interactions of 1700113I22Rik within a biological context.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR (mechanistic target of rapamycin), a protein kinase that plays a key role in regulating cell growth, proliferation, and protein synthesis. Rapamycin binds to mTOR and inhibits its activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent PI3K (phosphoinositide 3-kinase) inhibitor, affecting cell growth and survival signaling pathways. Wortmannin inhibits PI3K by covalently binding to its active site, disrupting PI3K-mediated signaling. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum inhibitor of protein kinases. Staurosporine inhibits various kinases by competing for ATP binding sites, blocking phosphorylation reactions, and affecting multiple cellular processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor that impacts various signaling pathways. LY294002 inhibits PI3K activity, disrupting downstream signaling events related to cell growth, proliferation, and survival. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Specifically inhibits p38 MAP kinase, a protein involved in stress responses and inflammation. SB203580 binds to the ATP pocket of p38 MAP kinase, preventing its activation and downstream signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK (mitogen-activated protein kinase kinase), which acts upstream of ERK (extracellular signal-regulated kinase) in the MAPK pathway. PD98059 blocks MEK activation and the subsequent phosphorylation of ERK. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK (c-Jun N-terminal kinase), influencing apoptosis and cellular differentiation. SP600125 competes with ATP for binding to JNK, inhibiting its kinase activity and downstream signaling pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Acts on DNA methylation, affecting gene expression. 5-Azacytidine is incorporated into DNA during replication, leading to DNA demethylation, changes in gene expression, and potential disruption of cellular processes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that affects chromatin structure and gene expression. Trichostatin A inhibits HDAC enzymes, leading to histone hyperacetylation, altered chromatin accessibility, and changes in gene transcription. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Inhibits the Hedgehog signaling pathway. Cyclopamine interferes with the function of Smoothened, a protein in the Hedgehog pathway, disrupting downstream signaling and affecting cellular processes regulated by this pathway. | ||||||