1600012H06Rik Activators
1600012H06Rik Activators are a collection of chemical compounds that influence various signaling cascades, potentially leading to the enhancement of 1600012H06Rik protein's functional activity without directly increasing its expression. Compounds such as Forskolin and Sildenafil work by increasing the levels of secondary messengers-cAMP and cGMP, respectively-thus activating PKA and cGMP-dependent protein kinases which may target and phosphorylate the 1600012H06Rik protein. Similarly, PMA acts as a PKC activator, and EGCG functions as a kinase inhibitor, each modulating distinct signaling pathways that could converge on the activation of the 1600012H06Rik protein.
The chemical class known as 1600012H06Rik Activators encompasses a range of compounds that serve as specific modulators of cellular processes by targeting the protein encoded by the gene 1600012H06Rik. These activators are characterized by their diverse chemical structures that are tailored to interact with the unique protein domains of the 1600012H06Rik protein. The interaction between these activators and their target can initiate a conformational change in the protein, which can, in turn, lead to an enhancement of the protein's activity. The mechanisms by which these activators function are rooted in their capacity to bind to distinct regions of the protein, thereby facilitating an increase in the protein's functional output. This increase in activity can result in the upregulation of downstream signaling pathways that are influenced by the 1600012H06Rik protein, thereby altering the biochemical landscape within the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin acts as an ionophore for calcium, increasing intracellular calcium concentration, which could activate calcium-dependent protein kinases that enhance 1600012H06Rik protein function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC) which can phosphorylate substrates that may include the 1600012H06Rik protein, potentially increasing its activity. | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $60.00 $192.00 $272.00 $883.00 | 1 | |
Spermine can modulate ion channels and may indirectly enhance the activity of the 1600012H06Rik protein by affecting the ionic environment and secondary messenger systems within the cell. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits several protein kinases, potentially reducing competitive inhibition and allowing 1600012H06Rik protein pathways to become more active. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates multiple signaling pathways, including the inhibition of NF-κB, which may lead to an indirect enhancement of the 1600012H06Rik protein's activity in specific contexts. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMPK, which may lead to the phosphorylation and activation of downstream proteins, potentially including the 1600012H06Rik protein. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, which may deacetylate and affect the activity of various proteins. This could indirectly enhance the activity of the 1600012H06Rik protein. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor, which could lead to a more relaxed chromatin structure around the 1600012H06Rik gene, indirectly enhancing protein activity post-translation. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside boosts NAD+ levels, potentially activating SIRT1 and other NAD+-dependent deacetylases, which may enhance the activity of the 1600012H06Rik protein indirectly. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride inhibits GSK-3, potentially leading to the activation of Wnt signaling pathway components, which could indirectly enhance the activity of the 1600012H06Rik protein. | ||||||