Date published: 2025-9-8

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Transaldolase 抗体 (C-5): sc-365449

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说明书
  • Transaldolase抗体(C-5)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Transaldolase的内部区域内的氨基酸182-211之间
  • 推荐用于 mouse, rat 和 human 来源的Transaldolase WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Transaldolase Antibody (C-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Transaldolase Antibody (C-5) 打包提供(请参阅下面的订购信息)。

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関連項目

适当的细胞生长、分化和存活依赖于一系列参与复杂氧化还原和代谢途径的酶。其中一种酶,转醛醇酶,有助于在戊糖磷酸途径(PPP)的非氧化阶段产生NADPH,对于维持代谢平衡非常重要。与其他几种酶结合,转醛醇酶通过产生核糖-5-磷酸和NADPH用于核酸和脂质生物合成,从而维持线粒体跨膜电位。转醛醇酶在精子磷酸戊糖途径中的作用非常重要,因为转醛醇酶的缺陷与精子结构和功能的丧失直接相关,导致男性不育。编码转醛醇酶的基因突变被认为在多发性硬化症中起作用,是肝脾肿大和皮肤毛细血管扩张的直接原因。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Transaldolase 抗体 (C-5) 参考文献:

  1. 转醛缩酶缺乏症患者的肺部表现。  |  Jassim, N., et al. 2014. JIMD Rep. 12: 47-50. PMID: 23846909
  2. 两名转醛缩酶缺乏症患者的临床和分子特征。  |  Tylki-Szymanska, A., et al. 2014. Eur J Pediatr. 173: 1679-82. PMID: 24497183
  3. 阿拉伯糖-5-磷酸共价抑制转醛缩酶。  |  Light, SH. and Anderson, WF. 2014. J Struct Funct Genomics. 15: 41-4. PMID: 24510200
  4. 抑制跨醛酶会损害线粒体呼吸并诱导秀丽隐杆线虫出现类似饥饿的长寿反应。  |  Bennett, CF., et al. 2017. PLoS Genet. 13: e1006695. PMID: 28355222
  5. 在obafluorin生物合成过程中,L-苏氨酸转醛缩酶是L-苏-β-羟基-α-氨基酸组装所必需的。  |  Scott, TA., et al. 2017. Nat Commun. 8: 15935. PMID: 28649989
  6. 转醛缩酶缺乏症患者对乙酰氨基酚的明显毒性。  |  Lee-Barber, J., et al. 2019. JIMD Rep. 44: 9-15. PMID: 29923087
  7. 对乙酰氨基酚诱导的肝衰竭患者转醛缩酶单基因功能不全。  |  Oaks, Z., et al. 2020. J Inherit Metab Dis. 43: 496-506. PMID: 31769880
  8. l-苏氨酸转醛缩酶活性由持续存在的催化中间体激活。  |  Kumar, P., et al. 2021. ACS Chem Biol. 16: 86-95. PMID: 33337128
  9. 杂合l-苏氨酸转醛缩酶ObiH催化可扩展、选择性的β-羟基-α-氨基酸合成。  |  Doyon, TJ., et al. 2022. Chembiochem. 23: e202100577. PMID: 34699683
  10. 硫代果糖转醛缩酶的结构和机理,硫代奎诺酮代谢的关键酶。  |  Snow, AJD., et al. 2023. Structure. 31: 244-252.e4. PMID: 36805128

订购信息

产品名称产品编号规格价格数量收藏夹

Transaldolase 抗体 (C-5)

sc-365449
200 µg/ml
$316.00

Transaldolase (C-5): m-IgG Fc BP-HRP 套装

sc-537805
200 µg Ab; 10 µg BP
$354.00

Transaldolase (C-5): m-IgGκ BP-HRP 套装

sc-535201
200 µg Ab; 40 µg BP
$354.00

Transaldolase (C-5): m-IgG1 BP-HRP 套装

sc-545367
200 µg Ab; 20 µg BP
$354.00

Transaldolase (C-5) 中和勝肽

sc-365449 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-365449 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Great immunofluorescence cytoplasmic stainingGreat immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-01-21
Rated 5 out of 5 by from Good Western Blot data of Transaldolase expressionGood Western Blot data of Transaldolase expression in non-transfected 293T, mouse Transaldolase transfected 293T and U-87 MG whole cell lysates. -SCBT QC
Date published: 2013-07-15
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Transaldolase 抗体 (C-5) is rated 5.0 out of 5 by 2.
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