Sp-Adenosine 3prime,5prime-cyclic monophosphorothioate triethylammonium salt CAS: 93602-66-5
MF: C10H11N5O5PS•C6H16N
MW: 446.46
A membrane permeable activator of cAMP dependent protein kinase I and II.

Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt (CAS 93602-66-5)

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备用名: Sp-Cyclic 3',5'-hydrogen phosphorothioate adenosine; Sp-cAMPS triethylammonium salt
应用; Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt is a membrane permeable activator of cAMP dependent protein kinase I and II
CAS号码: 93602-66-5
纯度: ≥98%
分子量: 446.46
分子式: C10H11N5O5PS•C6H16N
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Sp-Diastereomer of adenosine 3',5'-cyclic monophosphorothioate is a potent, membrane-permeable activator of PKA (cAMP dependent protein kinase I and II). Mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases. Exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP. Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt hydrate is an activator of Epac.

物理状态 :
Solid
溶解度 :
Soluble in water.
保存 :
Store at -20° C
熔点 :
212-213° C
光学活性 :
α22/D -25.43°, c = 0.99 in water
pK值 :
pKa: 1 (Predicted), pKb: 3.63 (Predicted)
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
PubChem CID :
57369926
MDL 号码 :
MFCD01459901
SMILES :
CC[NH+](CC)CC.C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=S)(O1)[O-]

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