Date published: 2025-9-7
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Somatostatin Antibody (G-10) - Western Blotting - Image 352420
体生长抑素抗体 (G-10): sc-55565. 对 TT 全细胞裂解液中生长抑素表达的 Western 印迹分析.
体生长抑素抗体 (G-10): sc-55565. 对 TT 全细胞裂解液中生长抑素表达的 Western 印迹分析.

Somatostatin 抗体 (G-10): sc-55565

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说明书
  • Somatostatin 抗体 G-10 是小鼠单克隆 IgG2b κ，Somatostatin抗体, 在44篇文献中引用，规格为200 µg/ml
  • 免疫human物种的Somatostatin的氨基酸1-106
  • Somatostatin 抗体 (G-10) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 Somatostatin
  • 抗Somatostatin抗体（G-10）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 还可偶联Alexa Fluor® 405 用于IF, IHC(P) 和FCM
  • 关于如何获取Somatostatin (G-10): sc-55565的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 是 Somatostatin 抗体 (G-10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Somatostatin 抗体 (G-10) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

体生长抑素抗体 (G-10) 是一种小鼠单克隆 IgG2b kappa 轻链抗体，可通过免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组织化学 (IHCP) 和酶联免疫吸附试验 (ELISA) 检测人源的体生长抑素蛋白。体生长抑素 (G-10) 抗体有非共轭型和多种共轭型，包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。体生长抑素是一种重要的调节激素，通过与高亲和性 G 蛋白偶联体生长抑素受体结合，在抑制多种次级激素释放方面发挥着重要作用。这种环状十四肽可抑制生长激素、胰岛素和胰高血糖素等主要激素的分泌，从而维持激素平衡。体生长抑素主要分布在下丘脑和胰腺中，这种激素可调节胰岛素的合成，突出了体生长抑素在葡萄糖代谢和整体内分泌功能中的重要性。体生长抑素有两种活性形式--体生长抑素-14 和体生长抑素-28--通过交替裂解单个前蛋白产生，在小脑的不同发育阶段有不同的表达模式。Somatostatin位于人类染色体3q27上，其表达对于调节中枢神经系统的神经传递率以及影响正常细胞和肿瘤细胞的增殖至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Somatostatin 抗体 (G-10) 参考文献:

  1. 生长抑素、生长抑素类似物和内皮细胞生长抑素基因转移对平滑肌细胞体外增殖的影响。  |  Sarkar, R., et al. 1999. J Vasc Surg. 29: 685-93. PMID: 10194497
  2. 生长抑素通过内化生长激素受体和减少生长激素受体mRNA的转录来调节肝脏生长激素敏感性。  |  Very, NM. and Sheridan, MA. 2007. Am J Physiol Regul Integr Comp Physiol. 292: R1956-62. PMID: 17272663
  3. 含有C-末端金刚烷的生长抑素类似物的合成及其抗增殖特性。  |  Miyazaki, A., et al. 2008. J Med Chem. 51: 5121-4. PMID: 18680358
  4. 生长抑素类似物通过细胞抑制和细胞毒性途径，以SSTR2依赖的方式抑制癌细胞增殖。  |  Zou, Y., et al. 2009. Oncol Rep. 21: 379-86. PMID: 19148511
  5. 生长抑素拮抗剂类似物可刺激大鼠的生长。  |  Spencer, GS. and Hallett, KG. 1985. Life Sci. 37: 27-30. PMID: 2861550
  6. 胰腺生长抑素样免疫反应抑制大鼠胃酸分泌。  |  Zyznar, E., et al. 1979. Life Sci. 24: 1195-9. PMID: 449619
  7. 颉颃物类似物可增加大鼠体内促生长激素, 胰岛素和胰高血糖素的释放。  |  Fries, JL., et al. 1982. Peptides. 3: 811-4. PMID: 6129618
  8. 生长抑素类似物在兔回肠和大鼠结肠中的结构-活性关系。  |  Rosenthal, LE., et al. 1983. J Clin Invest. 71: 840-9. PMID: 6131906
  9. 生长抑素样免疫反应存在于人类汗腺的树突状保护细胞中。  |  Johansson, O., et al. 1993. Peptides. 14: 401-3. PMID: 8097870
  10. 生长抑素可降低大鼠脑室周围核中生长抑素信使核糖核酸的水平。  |  Aguila, MC. 1998. Peptides. 19: 1573-9. PMID: 9864065

订购信息

产品名称产品编号规格价格数量收藏夹

Somatostatin 抗体 (G-10)

sc-55565
200 µg/ml
$316.00

Somatostatin (G-10): m-IgG Fc BP-HRP 套装

sc-525639
200 µg Ab; 10 µg BP
$354.00

Somatostatin 抗体 (G-10) AC

sc-55565 AC
500 µg/ml, 25% agarose
$416.00

Somatostatin 抗体 (G-10) HRP

sc-55565 HRP
200 µg/ml
$316.00

Somatostatin 抗体 (G-10) FITC

sc-55565 FITC
200 µg/ml
$330.00

Somatostatin 抗体 (G-10) PE

sc-55565 PE
200 µg/ml
$343.00

Somatostatin 抗体 (G-10) Alexa Fluor® 488

sc-55565 AF488
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 546

sc-55565 AF546
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 594

sc-55565 AF594
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 647

sc-55565 AF647
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 680

sc-55565 AF680
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 790

sc-55565 AF790
200 µg/ml
$357.00

Somatostatin 抗体 (G-10) Alexa Fluor® 405

sc-55565 AF405
200 µg/ml
$357.00

I want to stain delta cells in rat pancreata for IHC. Will this antibody bind rat somatostatin?

Asked by: JGPSCI
Thank you for your question. It would be helpful if you could call us directly at 800- 457-3801 option 2, allowing for a more interactive discussion of this and other related questions.
Answered by: Blake J
Date published: 2021-08-05

I'm looking to do some larger scale immunohistochemistry for somatostatin in brain. I am wondering if it is possible to get the free trial size aliquots for sc55565, sc74556, and sc25262? Hopefully, if one works with my procedures, I can order more.

Asked by: DavidK
Thank you for your question. Please contact your local distributor or technical service for further assistance.
Answered by: Dallas Tech Service
Date published: 2021-06-18

Is Somatostatin antibody (G-10, sc-55565) specific for the detection of Somatostation-28 and Somatostatin antibody (H-11, sc-74556) for the detection of Somatostatin-14. I get two different staining profile using these two antibodies in the same tissue.

Asked by: Nafiseh
Thank you for your question. These two monoclonal antibodies are raised against different, yet overlapping N-terminal recombinant protein sequences derived from human Somatostatin. The exact epitopes recognized by each monoclonal antibody have not been determined, and we do not have any information about which cleaved forms of Somatostatin 14 or 28 they may specifically detect. We would recommend checking some of the product citations using the antibodies to see if anyone else has observed a similar result. Please contact our Technical Service Department for further support.
Answered by: Technical Support
Date published: 2019-01-26

I need an antibody to make IF and WB from extracts of ovine pancreas. Do you know if this monoclonal antibody will work?

Asked by: Ronald
Somatostatin (G-10) monoclonal antibody, sc-55565, is recommended for detection of Somatostatin of human origin, and has not been tested for ovine samples. However, since the epitope used to make this antibody has 99% sequence identity to the ovine Somatostatin sequence (accession#O46688), I would expect this antibody to pick up Somatostatin in ovine samples without hesitation. Please feel free to contact technical support if you have any further questions!
Answered by: Tech Service
Date published: 2017-01-30

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Service 11
Date published: 2017-01-20
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Rated 5 out of 5 by from Mulitcolor IFExcellent staining of SST in multicolor IF of pig islet transplants in porcine liver.
Date published: 2024-04-23
Rated 4 out of 5 by from region dependentthe antibody works well at 1:1000 in rat's hippocampus and cortex but only stains fibers in the Ce and nothing in the BLA
Date published: 2020-01-10
Rated 5 out of 5 by from Great stainingTested a sample. Fluorescence immunohistochemistry (1:100) on 50 micron mouse brain slices perfused with 4% paraformaldehyde
Date published: 2018-11-15
Rated 5 out of 5 by from Very good antibody for Somatostatin neuron staininWe tried some antibodies for Somatostatin interneuron staining in mouse brain tissue. The staining is good.
Date published: 2018-05-04
Rated 5 out of 5 by from Very good AB for IFGreat for immunofluorescence in formalin-fixed for Mouse brain.
Date published: 2018-04-12
Rated 4 out of 5 by from works for me! with antigen retrievaladult mouse brain, fixed with pfa HIER, antigen retrieval at 100C in pH 6.0 citrate buffer 10 min primary1:300 in bsa blocking solution secondary alexa 488 note: looks great in hpc without hier good luck! P.S. to SCBT: I can't add a picture for some reason
Date published: 2017-12-06
Rated 5 out of 5 by from The product is good.Somatostatin Antibody had powerful band detected in a large number of cell lines in TT whole cell lysate.Recommend to everyone.
Date published: 2017-10-22
Rated 5 out of 5 by from The antibody is really greatSomatostatin antibody worked well in the human samples, intense and limpid, shows hight express in TT whole cell lysate.
Date published: 2017-10-17
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Somatostatin 抗体 (G-10) is rated 4.7 out of 5 by 15.
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