Date published: 2026-10-16
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SERCA3 Antibody (PL/IM430) - Western Blotting - Image 362854
SERCA3 抗体 (PL/IM430): sc-81759. HL-60 (A) 和 CCRF-CEM (B) 全细胞裂解液中 SERCA3 表达的 Western 印迹分析.
SERCA3 抗体 (PL/IM430): sc-81759. HL-60 (A) 和 CCRF-CEM (B) 全细胞裂解液中 SERCA3 表达的 Western 印迹分析.

SERCA3 抗体 (PL/IM430): sc-81759

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说明书
  • SERCA3抗体(PL/IM430)是小鼠单克隆IgG1 κ, 在7篇文献中引用，规格为200 µg/ml
  • 针对human来源的血小板细胞内膜
  • 抗-SERCA3 抗体 (PL/IM430) 推荐用于 WB, IP 和 IF，检测mouse, rat 和human 来源的 SERCA3
  • 抗SERCA3抗体（PL/IM430）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 还提供无叠氮化物的阻断测定试剂，sc-81759 L，200 µg/0.1 ml
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是SERCA3 Antibody (PL/IM430) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与SERCA3 Antibody (PL/IM430) 打包提供（请参阅下面的订购信息）。
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関連項目

额外SERCA抗体，包括SERCA1, SERCA2和SERCA3

SERCA3抗体（PL/IM430）是一种小鼠单克隆IgG1κ轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）和免疫荧光（IF）等方法检测小鼠、大鼠和人类样本中的SERCA3。抗SERCA3抗体（PL/IM430）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。SERCA3是肌浆或内质网钙ATP酶家族的一员，通过调节Ca2+进入细胞内储存区，在钙稳态中发挥着至关重要的作用，而钙稳态对于肌肉松弛和信号通路等各种细胞功能至关重要。与主要在肌肉组织中表达的SERCA1和SERCA2不同，SERCA3主要存在于非肌肉细胞中，例如血小板、淋巴细胞和肥大细胞，这凸显了其在免疫反应和细胞信号传导中的重要性。SERCA3的替代剪接以及与其他钙信号蛋白的相互作用，凸显了其在各种生理和病理过程中的潜在作用。SERCA3 单克隆抗体（PL/IM430）使研究人员能够对不同生物学环境中的钙调节动态获得宝贵的见解。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SERCA3 抗体 (PL/IM430) 参考文献:

  1. SERCA3 的异常表达与胃癌的发病机制, 侵袭, 转移和预后密切相关。  |  Xu, XY., et al. 2012. Tumour Biol. 33: 1845-54. PMID: 22948776
  2. VDAC1 和 SERCA3 在乳腺癌细胞中介导黄体酮触发的 Ca2+ 信号传导  |  Azeez, JM., et al. 2018. J Proteome Res. 17: 698-709. PMID: 29185755
  3. NAADP/SERCA3依赖性Ca2+储存途径可特异性控制早期内源性ADP分泌，从而增强血小板活化。  |  Feng, M., et al. 2020. Circ Res. 127: e166-e183. PMID: 32588751
  4. SERCA3 在泛癌症预后和免疫功能中的作用  |  Li, J., et al. 2022. J Oncol. 2022: 9359879. PMID: 36385955
  5. 胃肠道间质瘤中肌浆/内质网钙离子 ATP 酶 3 (SERCA3) 的表达。  |  Adle-Biassette, H., et al. 2024. Pathology. 56: 343-356. PMID: 38184384
  6. SERCA3 型细胞器 Ca2+ 泵。  |  Wuytack, F., et al. 1995. Biosci Rep. 15: 299-306. PMID: 8825032
  7. 血小板中第三种肌浆/内质网 Ca2+ ATP 酶（SERCA3）两种同工酶的表达。PL/IM430单克隆抗体可能识别SERCA3b异构体。  |  Bobe, R., et al. 1998. FEBS Lett. 423: 259-64. PMID: 9512369
  8. 钙 ATP 酶与呼吸肌功能  |  Aubier, M. and Viires, N. 1998. Eur Respir J. 11: 758-66. PMID: 9596133
  9. 小鼠 SERCA 3 基因 3' 端的特征和 mRNA 剪接变体的组织分布。  |  Ozog, A., et al. 1998. FEBS Lett. 427: 349-52. PMID: 9637255
  10. 表达快肌骨骼肌肌浆网 Ca2+-ATP 酶的转基因心脏心肌收缩力增强，Ca2+ 转运功能增强。  |  Loukianov, E., et al. 1998. Circ Res. 83: 889-97. PMID: 9797337
  11. 主动脉瓣狭窄诱导的大鼠心脏肥大中 Ca2+ 泵和 Ca2+ 释放通道的细胞分布。  |  Anger, M., et al. 1998. Circulation. 98: 2477-86. PMID: 9832495
  12. 替代剪接的人类 SERCA3 转录本的功能特征。  |  Poch, E., et al. 1998. Am J Physiol. 275: C1449-58. PMID: 9843705

订购信息

产品名称产品编号规格价格数量收藏夹

SERCA3 抗体 (PL/IM430)

sc-81759
200 µg/ml
$322.00

SERCA3 (PL/IM430): m-IgG Fc BP-HRP 套装

sc-528714
200 µg Ab; 10 µg BP
$361.00

SERCA3 (PL/IM430): m-IgGκ BP-HRP 套装

sc-521183
200 µg Ab, 40 µg BP
$361.00

SERCA3 (PL/IM430): m-IgG1 BP-HRP 套装

sc-543084
200 µg Ab; 20 µg BP
$361.00

SERCA3 抗体 (PL/IM430) L

sc-81759 L
200 µg/0.1 ml
$322.00

SERCA3 抗体 (PL/IM430) AC

sc-81759 AC
500 µg/ml, 25% agarose
$424.00

SERCA3 抗体 (PL/IM430) HRP

sc-81759 HRP
200 µg/ml
$322.00

SERCA3 抗体 (PL/IM430) FITC

sc-81759 FITC
200 µg/ml
$336.00

SERCA3 抗体 (PL/IM430) PE

sc-81759 PE
200 µg/ml
$349.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 488

sc-81759 AF488
200 µg/ml
$364.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 546

sc-81759 AF546
200 µg/ml
$364.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 594

sc-81759 AF594
200 µg/ml
$364.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 647

sc-81759 AF647
200 µg/ml
$364.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 680

sc-81759 AF680
200 µg/ml
$364.00

SERCA3 抗体 (PL/IM430) Alexa Fluor® 790

sc-81759 AF790
200 µg/ml
$364.00

I bought the L form of this antibody, sc-81759 L for blocking (neutralization). How long can I store this at in the refridgerator?

Asked by: jenniferc
The L form of the antibody should be stored at -20°C. Once thawed, we recommend using as soon as possible, although it is usually stable for up to 2 weeks at 4 degrees.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by Sciotti from Buon anticorpoSegnale ben visibile in 50 ug di lisato piastrinico, anche se leggermente "sporco". consigliato.
Date published: 2020-07-30
Rated 5 out of 5 by juberiya from Very good antibodyI bought this antibody for my paper work and it gave me good results
Date published: 2020-02-10
Rated 1 out of 5 by PaulaOslo from many unspecific bandstoo many unspecific bands, can't be sure which one is the right one, there seem to be one or two which go down slightly with SERCA3 knock-down but not very much
Date published: 2017-12-07
Rated 5 out of 5 by Limin from 抗体很好用SERCA3的抗体特异性不错！条带单一，没有杂带，信号不错，使用感觉不错，it's very good!
Date published: 2017-10-11
Rated 4 out of 5 by xz_bp from sc-81759 idenify SERCA3 in CNE2Dilute the sc-81759(sample 10ug/50ul) 1：250 in TBST with 5% nonfat dry milk ，4℃ overnight show obvious band of overexprssion.
Date published: 2017-02-15
Rated 3 out of 5 by Yujie Wang from The specificity of the antibody was poorThe specificity of the antibody was poor，Before the whole film is not hatched, did not find that can be identified。Later, I repeatedly verified the problem is not closed and two resistance。Overall is not very ideal。
Date published: 2017-01-04
Rated 4 out of 5 by JT from StrongStrong, robust signal at expected molecular weight for SERCA3 detected by WB using HL-60 whole cell lysate. -SCBT QC
Date published: 2015-04-10
Rated 5 out of 5 by CJ from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the human SERCA3 protein via Western Blot analysis. -SCBT QC
Date published: 2015-02-23
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SERCA3 抗体 (PL/IM430) is rated 3.9 out of 5 by 9.
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