Date published: 2025-9-6

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RNase T2 抗体 (E-5): sc-393729

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说明书
  • RNase T2 抗体 E-5 是小鼠单克隆 IgG1 κ,RNase T2抗体, 在4篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的代表全长RNase T2的氨基酸1-259
  • RNase T2 抗体 (E-5) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 RNase T2
  • 抗RNase T2抗体(E-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取RNase T2 (E-5): sc-393729免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是RNase T2 Antibody (E-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与RNase T2 Antibody (E-5) 打包提供(请参阅下面的订购信息)。

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関連項目

RNase T2抗体(E-5)是一种IgG1κ小鼠单克隆RNase T2抗体(也称为RNase T2抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的RNase T2蛋白。RNase T2抗体(E-5)既有非偶联型抗RNase T2抗体形式,也有多种偶联型抗RNase T2抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。核糖核酸酶是参与RNA代谢的普遍存在的酶,根据其结构、催化和生物学特性可分为几个家族。RNase T2(核糖核酸酶T2),也称为RNASE6PL,是一种由256个氨基酸组成的分泌型糖蛋白,属于高度保守的细胞质RNases家族。由于选择性剪接事件,RNase T2以两种异构体形式存在,充当II类肿瘤抑制因子。RNase T2普遍表达,被认为在调节肿瘤发生和转移中发挥重要作用。编码RNASE T2的基因发生突变会导致囊性白质脑病,这是一种具有无法区分的临床和神经放射学表型的常染色体隐性遗传病。RNASET2缺乏可能通过血管生成或RNA代谢干扰大脑发育和髓鞘形成。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RNase T2 抗体 (E-5) 参考文献:

  1. 卵巢癌中位于 6q27 染色体区的衰老诱导基因和 II 类肿瘤抑制基因的克隆和特征描述。  |  Acquati, F., et al. 2001. Oncogene. 20: 980-8. PMID: 11314033
  2. 卵巢癌细胞系染色体 6q27 带上的一个新的同源染色体缺失确定了一个假定的抑癌基因的位置。  |  Lin, H. and Morin, PJ. 2001. Cancer Lett. 173: 63-70. PMID: 11578810
  3. 人类 RNASET2 基因抑制肿瘤和转移。  |  Acquati, F., et al. 2005. Int J Oncol. 26: 1159-68. PMID: 15809705
  4. Rh/T2/S家族糖蛋白的第一个人类成员RNASET2的特征。  |  Campomenosi, P., et al. 2006. Arch Biochem Biophys. 449: 17-26. PMID: 16620762
  5. 具有抗肿瘤和抗血管生成特性的重组人 RNASET2 糖蛋白:表达, 纯化和表征。  |  Smirnoff, P., et al. 2006. Cancer. 107: 2760-9. PMID: 17109444
  6. 在黑色素瘤癌症模型中作为肿瘤颉颃作用基因的 RNASET2。  |  Monti, L., et al. 2008. Oncol Res. 17: 69-74. PMID: 18543608
  7. 染色体 6 编码的 RNaseT2 蛋白是一种细胞生长调节剂。  |  Liu, J., et al. 2010. J Cell Mol Med. 14: 1146-55. PMID: 19382914
  8. RNASET2缺陷性囊性白质脑病类似于先天性巨细胞病毒脑部感染。  |  Henneke, M., et al. 2009. Nat Genet. 41: 773-5. PMID: 19525954
  9. 通过酶切和化学探针推断的牛线粒体 tRNA(Phe)的高阶结构,其中缺少 '保守 '的 GG 和 T psi CG 序列。  |  Wakita, K., et al. 1994. Nucleic Acids Res. 22: 347-53. PMID: 7510390

订购信息

产品名称产品编号规格价格数量收藏夹

RNase T2 抗体 (E-5)

sc-393729
200 µg/ml
$316.00

RNase T2 (E-5): m-IgG Fc BP-HRP 套装

sc-530560
200 µg Ab; 10 µg BP
$354.00

RNase T2 (E-5): m-IgGκ BP-HRP 套装

sc-524066
200 µg Ab, 40 µg BP
$354.00

RNase T2 (E-5): m-IgG1 BP-HRP 套装

sc-544131
200 µg Ab; 20 µg BP
$354.00

RNase T2 抗体 (E-5) AC

sc-393729 AC
500 µg/ml, 25% agarose
$416.00

RNase T2 抗体 (E-5) HRP

sc-393729 HRP
200 µg/ml
$316.00

RNase T2 抗体 (E-5) FITC

sc-393729 FITC
200 µg/ml
$330.00

RNase T2 抗体 (E-5) PE

sc-393729 PE
200 µg/ml
$343.00

RNase T2 抗体 (E-5) Alexa Fluor® 488

sc-393729 AF488
200 µg/ml
$357.00

RNase T2 抗体 (E-5) Alexa Fluor® 546

sc-393729 AF546
200 µg/ml
$357.00

RNase T2 抗体 (E-5) Alexa Fluor® 594

sc-393729 AF594
200 µg/ml
$357.00

RNase T2 抗体 (E-5) Alexa Fluor® 647

sc-393729 AF647
200 µg/ml
$357.00

RNase T2 抗体 (E-5) Alexa Fluor® 680

sc-393729 AF680
200 µg/ml
$357.00

RNase T2 抗体 (E-5) Alexa Fluor® 790

sc-393729 AF790
200 µg/ml
$357.00

would you mind tell me, which terminal does this antibody bind?

Asked by: Z RY
Thank you for your question. sc-393729 is raised against amino acids 1-259 representing full length RNase T2 of mouse origin. Please contact our Technical Service Department if you have any other questions. Our Asian Technical Service team is available at (+86) 021-60936350 or asia@scbio.cn or by live chat on our website.
Answered by: Sen Li
Date published: 2024-09-23

I need to use an antibody to detect the protein in samples of monkey origin. Do you know if sc-393729: RNase T2 (E-5) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06

Has this antibody been validated for IHC staining?

Asked by: SciSH
Thank you for your question. We have not yet tested this mouse monoclonal antibody, RNase T2 (E-5): sc-393729 for immunohistochemistry. However, based on other data we do warranty this antibody for IF, or immunofluorescent staining on fresh or frozen tissues or cells, fixed in methanol or acetone. If you would be interested in receiving a free 10 µg sample of mouse monoclonal, RNase T2 (E-5): sc-393729, to test in your research application, please contact our Technical Service Department. Please call us toll free at (800) 457-3801 option 2, email scbt@scbt.com, or use our live chat.
Answered by: Technical Support
Date published: 2017-01-25
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Rated 3 out of 5 by from it is functionI can get clear bands as direction, but there are too many extra bands.
Date published: 2018-07-23
Rated 5 out of 5 by from Very good Western blot data of RNase T2 expressionVery good Western blot data of RNase T2 expression in SP2/0, I-11.15 and NCI-H460 whole cell lysates. -SCBT QC
Date published: 2014-03-25
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RNase T2 抗体 (E-5) is rated 4.0 out of 5 by 2.
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