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Relaxin Receptor 2 抗体 (H-4): sc-374293

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说明书
  • Relaxin Receptor 2 抗体 H-4 是小鼠单克隆 IgG1 κ,Relaxin Receptor 2抗体, 在1篇文献中引用,规格为200 µg/ml
  • 与human的Relaxin Receptor 2的细胞外结构域内的氨基酸81-230杂交
  • Relaxin Receptor 2 抗体 (H-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 Relaxin Receptor 2
  • 抗Relaxin Receptor 2抗体(H-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Relaxin Receptor 2 (H-4): sc-374293免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Relaxin Receptor 2 Antibody (H-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Relaxin Receptor 2 Antibody (H-4) 打包提供(请参阅下面的订购信息)。

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関連項目

Relaxin Receptor 2抗体(H-4)是一种IgG1 κ型小鼠单克隆Relaxin Receptor 2抗体(也称为Relaxin Receptor 2抗体),可通过WB、IP、IF和ELISA技术检测小鼠、大鼠和人类来源的Relaxin Receptor 2蛋白。Relaxin Receptor 2抗体(H-4)既可以是非偶联的抗Relaxin Receptor 2抗体形式,也可以是多种偶联形式的抗Relaxin Receptor 2抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。G蛋白偶联受体(GPRs)是一类跨膜受体蛋白家族,可将细胞外信号(配体结合)传递为细胞内信号(G蛋白激活)。Relaxin Receptor 2,也称为Relaxin/胰岛素样家族肽受体2、RXFP2、LGR8、GREAT、GPR106、INSL3R或RXFPR2,是一种富含亮氨酸重复的G蛋白偶联受体,可与Relaxins和INSL3(胰岛素样肽3)结合。Relaxin Receptor 2表达于脑、肌肉、子宫、肾、甲状腺、睾丸、骨髓和外周血细胞中,定位于细胞膜,包含十个LRR(富含亮氨酸重复序列)和一个LDL受体A类结构域。当Relaxin或INSL3与Relaxin Receptor 2结合时,腺苷酸(A)环化酶被激活,导致细胞内cAMP浓度增加。cAMP是一种关键的细胞内调节因子;它介导多种激素的活性,并在调节细胞活动中发挥重要作用。编码Relaxin Receptor 2的基因发生突变可导致隐睾症(睾丸下降受损),这是一种与不孕症和睾丸癌风险增加相关的疾病。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Relaxin Receptor 2 抗体 (H-4) 参考文献:

  1. 一种导致小鼠隐睾症的转基因插入物。  |  Overbeek, PA., et al. 2001. Genesis. 30: 26-35. PMID: 11353515
  2. 荷尔蒙松弛素激活孤儿受体。  |  Hsu, SY., et al. 2002. Science. 295: 671-4. PMID: 11809971
  3. INSL3/Leydig胰岛素样肽能激活对睾丸下降很重要的LGR8受体。  |  Kumagai, J., et al. 2002. J Biol Chem. 277: 31283-6. PMID: 12114498
  4. GREAT 基因突变会导致隐睾症。  |  Gorlov, IP., et al. 2002. Hum Mol Genet. 11: 2309-18. PMID: 12217959
  5. 人类隐睾症中的 INSL3-LGR8/GREAT 配体-受体对。  |  Ferlin, A., et al. 2003. J Clin Endocrinol Metab. 88: 4273-9. PMID: 12970298
  6. 弛缓素和 INSL3 受体的剪接变体揭示了意想不到的分子复杂性。  |  Muda, M., et al. 2005. Mol Hum Reprod. 11: 591-600. PMID: 16051677
  7. Peters Plus 综合征是由 B3GALTL(一种推定的糖基转移酶)突变引起的。  |  Lesnik Oberstein, SA., et al. 2006. Am J Hum Genet. 79: 562-6. PMID: 16909395
  8. 松弛素类配体-受体系统是肿瘤细胞的自分泌/旁分泌效应器,可调节癌症进展和组织侵袭性。  |  Klonisch, T., et al. 2007. Adv Exp Med Biol. 612: 104-18. PMID: 18161484

订购信息

产品名称产品编号规格价格数量收藏夹

Relaxin Receptor 2 抗体 (H-4)

sc-374293
200 µg/ml
$316.00

Relaxin Receptor 2 (H-4): m-IgG Fc BP-HRP 套装

sc-529714
200 µg Ab; 10 µg BP
$354.00

Relaxin Receptor 2 (H-4): m-IgGκ BP-HRP 套装

sc-522690
200 µg Ab, 40 µg BP
$354.00

Relaxin Receptor 2 (H-4): m-IgG1 BP-HRP 套装

sc-543646
200 µg Ab; 20 µg BP
$354.00

Relaxin Receptor 2 抗体 (H-4) AC

sc-374293 AC
500 µg/ml, 25% agarose
$416.00

Relaxin Receptor 2 抗体 (H-4) HRP

sc-374293 HRP
200 µg/ml
$316.00

Relaxin Receptor 2 抗体 (H-4) FITC

sc-374293 FITC
200 µg/ml
$330.00

Relaxin Receptor 2 抗体 (H-4) PE

sc-374293 PE
200 µg/ml
$343.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 488

sc-374293 AF488
200 µg/ml
$357.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 546

sc-374293 AF546
200 µg/ml
$357.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 594

sc-374293 AF594
200 µg/ml
$357.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 647

sc-374293 AF647
200 µg/ml
$357.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 680

sc-374293 AF680
200 µg/ml
$357.00

Relaxin Receptor 2 抗体 (H-4) Alexa Fluor® 790

sc-374293 AF790
200 µg/ml
$357.00

What is the recommended starting dilution for Western blot for sc-374293: Relaxin Receptor 2 (H-4) monoclonal antibody?

Asked by: Trav11
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22

Dear sir/madam, Are there any references that they have used this antibody (sc-374293)? I look forward to hearing from you ASAP? Best Regards, Saeed

Asked by: saeed
Thank you for your question. We are not aware of any product citations at this time for our mouse monoclonal antibody, Relaxin Receptor 2 (H-4): sc-374293. This is a relatively new antibody. We do warranty the antibody to work in the recommended applications of WB, IP, IF and ELISA on samples of human origin. If you purchase the antibody and it does not perform for you as expected in one of the recommended applications, then please contact our Technical Service department within one year of your purchase and we can provide you with a complimentary replacement antibody, or a refund.
Answered by: Technical Support
Date published: 2016-11-21
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Rated 5 out of 5 by from Produced nice Western blot data of RelaxinProduced nice Western blot data of Relaxin Receptor 2 expression in Jurkat and HeLa whole cell lysates. -SCBT QC
Date published: 2014-01-06
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Relaxin Receptor 2 抗体 (H-4) is rated 5.0 out of 5 by 1.
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