Relaxin Receptor 2 Activators
Relaxin Receptor 2 Activators belong to a distinctive chemical class that plays a crucial role in modulating cellular responses through the activation of the relaxin receptor subtype 2 (RXFP2). The relaxin receptor, a G protein-coupled receptor (GPCR), is predominantly expressed in various tissues, including reproductive organs and the cardiovascular system. This specific class of compounds exerts its effects by interacting with the receptor, leading to downstream signaling cascades. The relaxin receptor 2, when activated by these molecules, initiates a series of intracellular events that regulate cellular functions and contribute to the maintenance of homeostasis in target tissues.
Structurally, Relaxin Receptor 2 Activators are characterized by their ability to bind to specific sites on the relaxin receptor, inducing a conformational change that triggers receptor activation. This activation, in turn, stimulates various intracellular signaling pathways, such as the cyclic AMP (cAMP) and phosphatidylinositol 3-kinase (PI3K) pathways, among others. The precise mechanisms by which these activators elicit their effects may vary, but their commonality lies in their capacity to modulate the relaxin receptor 2 and influence downstream cellular responses. As a result, these compounds have garnered attention in the scientific community for their potential in elucidating the intricacies of cellular signaling and may serve as valuable tools for studying the physiological roles of the relaxin receptor 2 in different tissues and biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates Relaxin Receptor 2 indirectly by stimulating adenylyl cyclase, leading to an increase in intracellular cAMP levels. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
Functions as a cAMP analog, directly activating PKA, which may participate in pathways associated with Relaxin Receptor 2 activation. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Releases nitric oxide, indirectly activating Relaxin Receptor 2 by increasing intracellular cGMP levels. | ||||||
8-Bromo-cGMP | 51116-01-9 | sc-200316 sc-200316A | 10 mg 50 mg | $104.00 $354.00 | 7 | |
Acts as a cGMP analog, directly activating PKG, which may be involved in pathways associated with Relaxin Receptor 2 activation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
An ionophore that increases intracellular Ca2+ levels, indirectly activating Relaxin Receptor 2 through calcium-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates PKC and MAPK/ERK pathways, potentially initiating Relaxin Receptor 2-associated cellular responses. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $245.00 | 9 | |
Modulates PKC, potentially activating pathways linked to Relaxin Receptor 2. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Calcium ionophore that increases intracellular Ca2+ levels, indirectly activating Relaxin Receptor 2 through calcium-dependent signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that indirectly activates Relaxin Receptor 2 by modulating the PI3K/Akt pathway. | ||||||