Date published: 2025-9-6

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RASSF8 抗体 (4B1): sc-81934

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说明书
  • RASSF8 抗体 4B1 是小鼠单克隆 IgG2a (kappa轻链),RASSF8抗体,规格为100 µg/ml
  • 免疫human物种的重组RASSF8
  • 推荐用于 mouse, rat 和 human 来源的RASSF8 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取RASSF8 (4B1): sc-81934免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成RASSF8 抗体 (4B1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    RASSF8-抗体(4B1)是一种IgG2aκ小鼠单克隆RASSF8抗体(也称为RASSF8抗体),通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的RASSF8蛋白。RASSF8抗体(4B1)可作为非偶联的抗RASSF8抗体提供。RASSF8(Ras缔合(RalGDS/AF-6或RA)结构域(N-末端)家族成员8),也称为HoJ-1(癌相关蛋白HoJ-1),是N-末端RASSF家族的进化保守成员,其也由RASSF7、PAMCI(或RASSF9)和RASSF10组成。RASSF8含有一个N-末端RA结构域,被认为参与Ras信号通路。涉及编码RASSF8和Fibulin-1的基因的染色体相互易位与复杂形式的同指多指畸形有关,这种情况下,手或脚上通常有五个以上的手指,患者表现出手指和脚趾的带状或融合。此外,RASSF8能够在癌症中起到肿瘤抑制因子的作用,正如抑制凤尾鱼非依赖性生长的RASSF8的异位表达所表明的那样。这意味着功能性RASSF8的丧失可能与癌症的发展有关。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    RASSF8 抗体 (4B1) 参考文献:

    1. 纤维素-1基因(FBLN1)在与一种复杂类型的并趾畸形相关的t(12;22)中被破坏。  |  Debeer, P., et al. 2002. J Med Genet. 39: 98-104. PMID: 11836357
    2. 鉴定候选肺肿瘤抑制基因 RASSF8。  |  Falvella, FS., et al. 2006. Oncogene. 25: 3934-8. PMID: 16462760
    3. D12S1034 侧翼基因 RASSF8 和 BHLHB3 的常见多态性与肺腺癌风险没有缔合作用。  |  Falvella, FS., et al. 2007. Lung Cancer. 56: 1-7. PMID: 17194498
    4. RASSF7 是一个新的含 RAS 缔合作用域蛋白家族的成员,是完成有丝分裂所必需的。  |  Sherwood, V., et al. 2008. Mol Biol Cell. 19: 1772-82. PMID: 18272789

    订购信息

    产品名称产品编号规格价格数量收藏夹

    RASSF8 抗体 (4B1)

    sc-81934
    100 µg/ml
    $333.00

    Can sc-81934: RASSF8 (4B1) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: Dr Ninau Qelp
    Thank you for your question. Yes, sc-81934: RASSF8 (4B1) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 5 out of 5 by from Clear band and significant activityWe apply a free sample of the andibody three months ago, in fact, the anthbody worked well, thanks for SCBT!
    Date published: 2018-04-29
    Rated 5 out of 5 by from Positive signal in WB in HTPositive signal in WB in HT-1080 whole cell lysate and human testis tissue extract. -SCBT QC
    Date published: 2015-06-25
    Rated 5 out of 5 by from Robust signal in WB in HeLaRobust signal in WB in HeLa, NIH/3T3 and F9 whole cell lysates and mouse testis tissue extract. -SCBT QC
    Date published: 2015-05-13
    Rated 5 out of 5 by from Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human testis tissue. -SCBT QC
    Date published: 2015-04-19
    Rated 5 out of 5 by from Strong band in WB in HeLa whole cell lysateStrong band in WB in HeLa whole cell lysate. -SCBT QC
    Date published: 2015-03-03
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    RASSF8 抗体 (4B1) is rated 5.0 out of 5 by 5.
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