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PSA/KLK3/Kallikrein 3/Prostate Specific Antigen Antibody (A67-B/E3) - Western Blotting - Image 158432
PSA 抗体 (A67-B/E3): sc-7316. βME 处理的人前列腺组织提取物中 PSA 表达的 Western 印迹分析.
PSA 抗体 (A67-B/E3): sc-7316. βME 处理的人前列腺组织提取物中 PSA 表达的 Western 印迹分析.

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3): sc-7316

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说明书
  • PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 A67-B/E3 是小鼠单克隆 IgG1 κ，PSA/KLK3/Kallikrein 3/Prostate Specific Antigen抗体, 在91篇文献中引用，规格为200 µg/ml
  • 针对氨基酸1-261的，代表全长PSA p30的human起源
  • PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体（A67-B/E3）推荐用于通过 WB, IP, IF, IHC(P) 和 ELISA 检测 PSA 的 human 来源
  • 抗PSA/KLK3/Kallikrein 3/Prostate Specific Antigen抗体（A67-B/E3）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PSA/KLK3/Kallikrein 3/Prostate Specific Antigen (A67-B/E3): sc-7316的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 PSA 抗体包括 ACT

PSA抗体（A67-B/E3）是一种鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、石蜡包埋切片免疫组织化学（IHCP）和酶联免疫吸附测定（ELISA）检测人源前列腺特异性抗原（PSA）。抗-PSA抗体（A67-B/E3）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。前列腺特异性抗原，也称为与激肽酶相关的蛋白酶3（KLK3），是一种主要在前列腺中产生的丝氨酸蛋白酶，其中PSA通过水解精液浆中的主要蛋白精液凝胶蛋白I，在精液液化中起着至关重要的作用。这种酶活性对于男性生育能力至关重要，因为PSA可使精子在射精后自由游动。血液中PSA水平升高通常与前列腺癌有关，因此PSA是早期发现和监测前列腺癌的重要生物标志物。此外，PSA在其他组织（包括乳腺组织）中也存在，这表明PSA在多种癌症中可能发挥重要作用。PSA单克隆抗体（A67-B/E3）可在多种应用中精确检测这种重要蛋白质，因此PSA（A67-B/E3）抗体成为研究人员研究前列腺健康和疾病的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) 参考文献:

  1. 女性前列腺特异性抗原（PSA）。  |  Yu, H. and Berkel, H. 1999. J La State Med Soc. 151: 209-13. PMID: 10234897
  2. 人类前列腺特异性抗原：与丝氨酸蛋白酶在结构和功能上的相似性。  |  Watt, KW., et al. 1986. Proc Natl Acad Sci U S A. 83: 3166-70. PMID: 2422647
  3. 人类前列腺特异性抗原 cDNA 的分子克隆。  |  Lundwall, A. and Lilja, H. 1987. FEBS Lett. 214: 317-22. PMID: 2436946
  4. 前列腺特异性抗原检测在前列腺癌诊断后的局限性。  |  Caram, ME., et al. 2016. Eur Urol. 70: 209-10. PMID: 26776937
  5. 基于转导元件的前列腺特异性抗原（PSA）生物传感器的新分类。  |  Najeeb, MA., et al. 2017. Talanta. 168: 52-61. PMID: 28391865
  6. 人精浆中一种糖蛋白--γ-精蛋白的分离, 特征和氨基酸序列。  |  Schaller, J., et al. 1987. Eur J Biochem. 170: 111-20. PMID: 3691515
  7. 前列腺特异性抗原（PSA）的生物化学。  |  Malm, J. and Lilja, H. 1995. Scand J Clin Lab Invest Suppl. 221: 15-22. PMID: 7544481
  8. 通过基于前列腺特异性抗原的筛查，可提高器官封闭性前列腺癌的检测率。  |  Catalona, WJ., et al. 1993. JAMA. 270: 948-54. PMID: 7688438
  9. 前列腺特异性抗原的生化特征和最新生物学知识。  |  Seregni, E., et al. 1996. Tumori. 82: 72-7. PMID: 8623511
  10. 精囊分泌的人类精子活力抑制剂活性前体的纯化和特征：与精蛋白凝集素的同一性。  |  Robert, M. and Gagnon, C. 1996. Biol Reprod. 55: 813-21. PMID: 8879494
  11. 前列腺特异性抗原在其主要生理底物--精子活力抑制剂前体/前列腺素 I--上的蛋白水解活性特征。  |  Robert, M., et al. 1997. Biochemistry. 36: 3811-9. PMID: 9092810
  12. 前列腺特异性抗原与前列腺癌的早期检测。  |  Chu, TM. 1997. Tumour Biol. 18: 123-34. PMID: 9222310

订购信息

产品名称产品编号规格价格数量收藏夹

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3)

sc-7316
200 µg/ml
$316.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen (A67-B/E3): m-IgG Fc BP-HRP 套装

sc-528174
200 µg Ab; 10 µg BP
$354.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen (A67-B/E3): m-IgGκ BP-HRP 套装

sc-520491
200 µg Ab, 40 µg BP
$354.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen (A67-B/E3): m-IgG1 BP-HRP 套装

sc-542800
200 µg Ab; 20 µg BP
$354.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) AC

sc-7316 AC
500 µg/ml, 25% agarose
$416.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) HRP

sc-7316 HRP
200 µg/ml
$316.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) FITC

sc-7316 FITC
200 µg/ml
$330.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) PE

sc-7316 PE
200 µg/ml
$343.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 488

sc-7316 AF488
200 µg/ml
$357.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 546

sc-7316 AF546
200 µg/ml
$357.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 594

sc-7316 AF594
200 µg/ml
$357.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 647

sc-7316 AF647
200 µg/ml
$357.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 680

sc-7316 AF680
200 µg/ml
$357.00

PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) Alexa Fluor® 790

sc-7316 AF790
200 µg/ml
$357.00

I need biotin Anti-PSA antibody, do you have this option?

Asked by: Anonymous
Thank you for your question. A biotin-conjugated version of the antibody can be supplied as a special order product. Please contact technical service so that a special order can be arranged for you.
Answered by: Technical Support Europe
Date published: 2020-10-28

rat 에서 PSA 를 검출하고 싶은데 이 antibody는 human만 검출이 됩니까? 그렇다면 혹시 rat 까지 검출할 수 있는 PSA antibody가 있습니까?

Asked by: minju6021
산타크루즈바이오테크놀러지에 문의 주셔서 감사합니다. 죄송합니다,모든 PSA 항체 제품은 human에만 검출하는 것을 추천합니다. 다른 문제 있으시면 기술지원팀에 연락하셔서 전화:86 21-60936350 이메일: asia@scbio.cn 또는 온라인문의로 문의하시면 됩니다. Thank you for your question.All the PSA antibodies are just recommended in human sample.If you have any other question ,please contact our Technical Service Department at email asia@scbio.cn,call us directly at  (86 21) 6093-6350, or contact us by live chat.
Answered by: Technical Service 11
Date published: 2019-01-29

I would like to use this antibody for a double stain I am planning. How can that work with only mouse monoclonal antibodies?

Asked by: Cweed
We recommend using conjugated primary antibodies. This product, sc-7316, is available directly conjugated to FITC, AF488, and AF 647.
Answered by: TechService7
Date published: 2016-12-30
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Rated 2 out of 5 by from Discrete signalNot really good for detection in wb in our cancer cells model
Date published: 2020-11-10
Rated 5 out of 5 by from Great for ParaffinReceived this as a sample. We tested this using FFPE human hyperplasia prostate and got results first try. We used HIER sodium citrate pH 6.0 at 1:250.
Date published: 2017-11-29
Rated 4 out of 5 by from Good ab for IFI used this Ab on FFPE human prostate tissue sections. The first time I did EDTA/Tris antigen retrieval in a pressure cooker at 100C for 10 minutes and had some non-specific binding. I tried again with Sodium Citrate at 100C for 5 minutes and was able to get a more specific stain at 1:300. The staining is much brighter than the 2ndary only control (left).
Date published: 2017-10-20
Rated 5 out of 5 by from Excellent antibodyThis antibody works very well for IHC and Western blotting.
Date published: 2017-10-20
Rated 5 out of 5 by from anti PSA purchaseThe antibody works really good. It was applied to a APTES modified glutaric anhydried surface and the immobilization result was really satisfactory!
Date published: 2017-10-04
Rated 5 out of 5 by from works very wellThat it can be used for detect human prostate tissue, very good antibody, I use dilution 1:500.
Date published: 2017-09-07
Rated 4 out of 5 by from Very good Antibody for IHCI used this antibody for IHC of tumor tissues, it works very good, but the specificity need to be improved.
Date published: 2017-07-23
Rated 5 out of 5 by from Good antibodyIt's very good for IHC stanning of mouse xeno tumor tissue from human origin
Date published: 2017-07-11
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PSA/KLK3/Kallikrein 3/Prostate Specific Antigen 抗体 (A67-B/E3) is rated 4.7 out of 5 by 19.
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