Date published: 2025-9-9

021-6093-6350

SCBT Portrait Logo
Seach Input

Pma1p 抗体 (40B7): sc-57978

4.5(2)
寫評論提問

说明书
  • Pma1p 抗体 40B7 是小鼠单克隆 IgM,Pma1p抗体, 在4篇文献中引用,规格为250 µl supernatant
  • 针对S. cerevisiae来源的核制剂
  • 推荐用于 y 来源的Pma1p WB 和 IF检测
  • 目前,我们还没有完成Pma1p 抗体 (40B7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

関連項目

Pma1p抗体(40B7)是一种IgM小鼠单克隆Pma1p抗体(也称为Pma1p抗体),可通过WB和IF检测酿酒酵母来源的Pma1p蛋白。Pma1p抗体(40B7)可作为非偶联抗Pma1p抗体使用。Pma1p代表酵母中的主要质膜质子ATP酶,它是分泌途径中最丰富和最持久的多主题蛋白之一。Pma1p是一种酶,在环境压力不存在或存在的情况下都具有关键的生理作用。Pma1p在脂质筏中产生后到达细胞表面,脂质筏是膜微域,其饱和脂肪酸和固醇的含量高于膜的其他部分。脂质筏在许多细胞过程中发挥关键作用,例如信号传导、细胞分裂和对环境的反应,并且这些筏含有重要的蛋白质。Pma1p的寡聚化有助于其分配到脂质筏中并将其运输到细胞表面。Sec24p同源物Lst1p直接将Pma1p传递到COPII囊泡中,以便最终导出。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Pma1p 抗体 (40B7) 参考文献:

  1. 脂质筏在酵母将蛋白质运送到细胞表面的生物合成过程中发挥作用。  |  Bagnat, M., et al. 2000. Proc Natl Acad Sci U S A. 97: 3254-9. PMID: 10716729
  2. 在酿酒酵母中,Lst1p 和 Sec24p 合作将质膜 ATPase 分选到 COPII 囊泡中。  |  Shimoni, Y., et al. 2000. J Cell Biol. 151: 973-84. PMID: 11086000
  3. 质膜质子 ATP 酶 Pma1p 在酵母体内的表面输送需要筏状结合。  |  Bagnat, M., et al. 2001. Mol Biol Cell. 12: 4129-38. PMID: 11739806
  4. 酵母内质网中寡聚 H+-ATP 酶 Pma1p 的形成需要神经酰胺的生物合成。  |  Lee, MC., et al. 2002. J Biol Chem. 277: 22395-401. PMID: 11950838
  5. Can1p 在稳定结构域中的分布反映了活体 S. cerevisiae 细胞质膜内蛋白质的横向分离。  |  Malinska, K., et al. 2004. J Cell Sci. 117: 6031-41. PMID: 15536122
  6. 将新合成的质膜 ATPase 运送到酵母细胞表面需要合成具有超长链脂肪酸的鞘脂,但不需要麦角固醇。  |  Gaigg, B., et al. 2005. J Biol Chem. 280: 22515-22. PMID: 15817474
  7. 酵母的多胺耐受机制:新的调节器和见解。  |  Porat, Z., et al. 2005. Cell Mol Life Sci. 62: 3106-16. PMID: 16374585
  8. 白念珠菌抗洗涤剂膜的蛋白质组分析。  |  Insenser, M., et al. 2006. Proteomics. 6 Suppl 1: S74-81. PMID: 16534748
  9. 酵母中新合成的质膜 ATPase 需要含极长链脂肪酸的脂类而非鞘磷脂本身来进行筏结合和稳定的表面运输。  |  Gaigg, B., et al. 2006. J Biol Chem. 281: 34135-45. PMID: 16980694

订购信息

产品名称产品编号规格价格数量收藏夹

Pma1p 抗体 (40B7)

sc-57978
250 µl supernatant
$316.00

What is the concentration of Pma1p (40B7): sc-57978 monoclonal antibody?

Asked by: jerojero
Thank you for your question. The concentration of Pma1p (40B7): sc-57978 has not been characterized. We provide this antibody as 250 µl of supernatant
Answered by: Technical Support
Date published: 2017-03-24

I am interested in your anti-Pma1p Antibody (40B7): sc-57978. What antigen was used to immunize the mouse? If the antigen was not a peptide, do you know what part of the protein is recognized by the antibody? It is extracellular or intracellular?

Asked by: gpesce
Thank you for your question. This is a mouse monoclonal IgM, Pma1p Antibody (40B7): sc-57978, that was raised against nuclear protein preparations of yeast origin. As a reference, the accession number for the Pma1p yeast protein sequence is raised CAA96708. Unfortunately, the exact epitope recognized by this monoclonal antibody has not been determined. It is unknown whether the epitope is extracellular or intracellular.
Answered by: Technical Support
Date published: 2020-11-25
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_57978, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 105ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Good for Western BlotThis antibody has been used for western blotting in published research. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from This antibody was used in a publication for IFThis antibody was used in a publication for IF, WB on yeast The hgt1- yeast strain and its parental yeast strain - SCBT Publication Review
Date published: 2013-07-13
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_57978, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 12ms
  • REVIEWS, PRODUCT
Pma1p 抗体 (40B7) is rated 4.5 out of 5 by 2.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_57978, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 78ms
  • REVIEWS, PRODUCT