Date published: 2025-9-7
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PARP1 Antibody (D-1) - Western Blotting - Image 349955
PARP-1 抗体 (D-1): sc-365315. WEHI-231 (A) 和 KNRK (B) 全细胞裂解液中 PARP-1 表达的 Western 印迹分析.
PARP1 Antibody (D-1) - Western Blotting - Image 349955
PARP-1 抗体 (D-1): sc-365315. WEHI-231 (A) 和 KNRK (B) 全细胞裂解液中 PARP-1 表达的 Western 印迹分析.
PARP1 Antibody (D-1) - Western Blotting - Image 379074
PARP1抗体（D-1）：sc-365315。Western blot分析RAW 264.7全细胞裂解液中PARP-1的表达。
PARP1 Antibody (D-1) - Western Blotting - Image 139135
PARP-1 抗体 (D-1): sc-365315. 在 NIH/3T3 核提取物中检测 PARP-1 表达的 Western 印迹分析.
PARP-1 抗体 (D-1): sc-365315. WEHI-231 (A) 和 KNRK (B) 全细胞裂解液中 PARP-1 表达的 Western 印迹分析.

PARP1 抗体 (D-1): sc-365315

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寫評論提問

说明书
  • PARP1抗体(D-1)是小鼠单克隆IgG1 κ, 在28篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于mouse物种的PARP的N-terminus的氨基酸1-27之间
  • 推荐用于 mouse, rat 和 human 来源的full-length PARP-1 and the N-terminal cleavage product of PARP-1 WB, IP, IF 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-365315 X, 200 µg/0.1 ml)
  • 看 PARP1 (F-2): sc-8007，可查看有标记的 PARP1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是PARP1 Antibody (D-1) for WB applications. 的首选辅助检测试剂，这些试剂现与PARP1 Antibody (D-1) 打包提供（请参阅下面的订购信息）。

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研究信息

関連項目

附加PARP抗体，包括pADPr, PARP-1, PARP-10, PARP-14, PARP-2, PARP-3和PARP-4

多聚（ADP-核糖）聚合酶-1（PARP-1），也称为PARP，是一种核DNA结合锌指蛋白，可影响DNA修复、DNA复制、染色质结构调制和细胞凋亡。作为对遗传毒性应激的响应，PARP-1催化ADP-核糖单位从NAD（+）转移到包括染色质在内的许多受体分子上。PARP-1识别DNA链中断，并能与RNA形成复合物并负调控转录。放线菌素D和依托泊苷依赖性诱导的半胱天冬酶介导PARP-1裂解成p89片段，该片段进入细胞质。凋亡诱导因子（AIF）从线粒体到细胞核的转位依赖于PARP-1，并且是PARP-1依赖性细胞死亡所必需的。PARP-1的缺乏导致由于染色体融合和异倍体频率的增加而引起的染色体不稳定性，这表明多聚（ADP-核糖基）化有助于有效维持基因组完整性。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

PARP1 抗体 (D-1)

sc-365315
200 µg/ml
$316.00

PARP1 (D-1): m-IgG Fc BP-HRP 套装

sc-540328
200 µg Ab; 10 µg BP
$354.00

PARP1 (D-1): m-IgG1 BP-HRP 套装

sc-542045
200 µg Ab; 20 µg BP
$354.00

PARP1 (D-1) 中和勝肽

sc-365315 P
100 µg/0.5 ml
$68.00

PARP1 抗体 (D-1) X

sc-365315 X
200 µg/0.1 ml
$316.00

What application is the blocking peptide sc-365315 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Great features!I bought it often. It works very well. I recommend this product.
Date published: 2018-08-16
Rated 2 out of 5 by from relatively weak antibody for WB of mouse tissuescompared side-by-side with Santa Cruz B10 anti-PARP1 Ab, the D-1 antibody gives a much weaker signal (at 1:500 dilution) on WB of 30ug mouse tissue.
Date published: 2017-07-06
Rated 5 out of 5 by from Excellent!This antibody is great in western blot analysis of PARP-1 expression in NIH/3T3 nuclear extract.
Date published: 2017-01-30
Rated 4 out of 5 by from Used in WB at 1:500 and worked fineUsed in WB at 1:500 and worked fine.
Date published: 2015-09-24
Rated 3 out of 5 by from Okay results in WBOkay results in WB
Date published: 2015-03-31
Rated 5 out of 5 by from Western blot publication with human prostateWestern blot publication with human prostate cancer LNCaP cells. -SCBT Publication Review
Date published: 2015-02-25
Rated 5 out of 5 by from Publishable Western blot results using RAW264Publishable Western blot results using RAW264.7 samples. -SCBT Publication Review
Date published: 2015-02-12
Rated 5 out of 5 by from Performs well in WesternPerforms well in Western, good signal with HT29 cells. -SCBT Publication Review
Date published: 2015-01-16
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PARP1 抗体 (D-1) is rated 4.3 out of 5 by 10.
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