PAPSS 1 Antibody (A-8): sc-376306

PAPSS 1 Antibody (A-8) is a mouse monoclonal IgG1 antibody that detects PAPSS 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PAPSS 1, also known as bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthetase, plays a crucial role in sulfate assimilation within the sulfur metabolism pathway, acting as the sole source of sulfate in mammals. PAPSS 1 is essential for the biosynthesis of sulfated L-selectin ligands in endothelial cells, which are vital for cell adhesion and signaling processes. Proper functioning of PAPSS 1 is critical for maintaining normal physiological processes, as PAPSS 1 regulates the availability of sulfate for various biochemical reactions, including the synthesis of glycosaminoglycans and other sulfated macromolecules. PAPSS 1 is predominantly expressed in the pancreas, liver, testis, thymus, kidney, prostate, ovary, and small intestine, highlighting PAPSS 1′s importance in diverse biological functions across different tissues. Anti-PAPSS 1 antibody (A-8) specificity and sensitivity make this product an invaluable tool for researchers studying PAPSS 1′s role in health and disease, particularly in the context of sulfate metabolism and cellular processes.

The preferred PAPSS 1 antibody is PAPSS 1 Antibody (A-2): sc-376244.