Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

NPY 抗体 (F-6): sc-133080

4.3(9)
寫評論提問

说明书
  • NPY 抗体 F-6 是小鼠单克隆 IgG2a κ,NPY抗体, 在27篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长NPY的氨基酸1-97
  • NPY 抗体 (F-6) 推荐用于WB, IP, IF 和 ELISA,检测mouse, rat, human 来源的 NPY
  • 抗NPY抗体(F-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取NPY (F-6): sc-133080免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是NPY Antibody (F-6) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与NPY Antibody (F-6) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

NPY抗体(F-6)是一种IgG2a κ小鼠单克隆NPY抗体(也称为前神经肽Y抗体、神经肽Y抗体或PYY4抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的NPY蛋白。 NPY抗体(F-6)可作为非偶联抗NPY抗体形式以及多种偶联形式的抗NPY抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。 NPY激素家族由NPY、PP和肽YY组成。 NPY(神经肽Y)是一种由多脯氨酸片段和两亲性α-螺旋组成的36个氨基酸的蛋白质。 NPY与胰腺多肽基因(PP)具有50%的氨基酸同源性。 NPY在整个中枢和周围神经系统中表达,特别是在皮质深层和白质中的较小细胞体中。 NPY与G蛋白偶联受体的Y受体家族相互作用。 NPY与NPY受体Y1相互作用,以增加下丘脑中的促肾上腺皮质激素水平并降低去甲肾上腺素水平。通过在下丘脑中的相互作用,NPY通过刺激食物摄入在能量平衡的调节中发挥重要作用。 NPY通过增加白色脂肪组织中的脂蛋白脂酶活性来促进能量储存。亮氨酸7至脯氨酸7多态性与酒精偏好的增加和胆固醇代谢的减少有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NPY 抗体 (F-6) 参考文献:

  1. 神经肽 Y 家族配体与受体相互作用的分子特征。  |  Cabrele, C. and Beck-Sickinger, AG. 2000. J Pept Sci. 6: 97-122. PMID: 10759209
  2. 中年男性的神经肽 Y 多态性与饮酒量。  |  Kauhanen, J., et al. 2000. Am J Med Genet. 93: 117-21. PMID: 10869113
  3. NPY Y1受体对体外大鼠下丘脑的促肾上腺皮质激素释放因子和去甲肾上腺素溢出具有相反的作用。  |  Hastings, JA., et al. 2001. Brain Res. 890: 32-7. PMID: 11164766
  4. 用互补 RNA 探针原位杂交法确定人大脑皮层神经元中神经肽 Y mRNA 的位置。  |  Terenghi, G., et al. 1987. Proc Natl Acad Sci U S A. 84: 7315-8. PMID: 2444979
  5. 神经肽Y(NPY)和创伤后应激障碍(PTSD):最新转化研究。  |  Schmeltzer, SN., et al. 2016. Exp Neurol. 284: 196-210. PMID: 27377319
  6. 神经肽Y(NPY)作为神经退行性疾病的治疗靶点。  |  Duarte-Neves, J., et al. 2016. Neurobiol Dis. 95: 210-24. PMID: 27461050
  7. 神经肽Y(NPY)通过促进上皮细胞增殖来促进炎症诱导的肿瘤发生。  |  Jeppsson, S., et al. 2017. Am J Physiol Gastrointest Liver Physiol. 312: G103-G111. PMID: 27856419
  8. 神经肽Y(NPY)在酒精和药物滥用疾病中的作用。  |  Robinson, SL. and Thiele, TE. 2017. Int Rev Neurobiol. 136: 177-197. PMID: 29056151
  9. 编码胰腺多肽和神经肽 Y 的基因位于人类第 17 和 7 号染色体上。  |  Takeuchi, T., et al. 1986. J Clin Invest. 77: 1038-41. PMID: 3753985
  10. 编码神经肽酪氨酸的人类 cDNA 的克隆, 特征和 DNA 序列。  |  Minth, CD., et al. 1984. Proc Natl Acad Sci U S A. 81: 4577-81. PMID: 6589611
  11. 人类神经肽 Y 的溶液结构。  |  Monks, SA., et al. 1996. J Biomol NMR. 8: 379-90. PMID: 9008359
  12. 神经肽 Y 信号肽中亮氨酸(7)-脯氨酸(7)多态性与高血清胆固醇和低密度脂蛋白胆固醇水平的关系。  |  Karvonen, MK., et al. 1998. Nat Med. 4: 1434-7. PMID: 9846584

订购信息

产品名称产品编号规格价格数量收藏夹

NPY 抗体 (F-6)

sc-133080
200 µg/ml
$316.00

NPY (F-6): m-IgG Fc BP-HRP 套装

sc-528742
200 µg Ab; 10 µg BP
$354.00

NPY (F-6): m-IgGκ BP-HRP 套装

sc-521225
200 µg Ab, 40 µg BP
$354.00

NPY 抗体 (F-6) AC

sc-133080 AC
500 µg/ml, 25% agarose
$416.00

NPY 抗体 (F-6) HRP

sc-133080 HRP
200 µg/ml
$316.00

NPY 抗体 (F-6) FITC

sc-133080 FITC
200 µg/ml
$330.00

NPY 抗体 (F-6) PE

sc-133080 PE
200 µg/ml
$343.00

NPY 抗体 (F-6) Alexa Fluor® 488

sc-133080 AF488
200 µg/ml
$357.00

NPY 抗体 (F-6) Alexa Fluor® 546

sc-133080 AF546
200 µg/ml
$357.00

NPY 抗体 (F-6) Alexa Fluor® 594

sc-133080 AF594
200 µg/ml
$357.00

NPY 抗体 (F-6) Alexa Fluor® 647

sc-133080 AF647
200 µg/ml
$357.00

NPY 抗体 (F-6) Alexa Fluor® 680

sc-133080 AF680
200 µg/ml
$357.00

NPY 抗体 (F-6) Alexa Fluor® 790

sc-133080 AF790
200 µg/ml
$357.00

Good day, I would like to ask if this antibody has been used for rat tissue as well as whether or not it is validated for Western Blotting. Many thanks.

Asked by: J2699
Thank you for your question. sc-133080 is for mouse rat and human . The recommended applications are : WB, IP, IF, ELISA .
Answered by: BlakeJ
Date published: 2023-03-16

NPY Antibody (F-6) sc-133080 is this antibody has been tested against PYY?

Asked by: Amal
Thank you for your question. We have not tested this antibody against PYY.
Answered by: Technical Support
Date published: 2019-07-13

What is the recommended starting dilution for Western blot for sc-133080: NPY (F-6) monoclonal antibody?

Asked by: Trav11
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
  • y_2025, m_8, d_28, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_3
  • loc_zh_CN, sid_133080, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 106ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Very goodGreat for immunofluorescence in formalin-fixed for Mouse brain.
Date published: 2018-04-12
Rated 5 out of 5 by from The product is good.WB detected very strong bands and clear without background.We harvested very large when using antibody 1:1000 to whole cell lysate.
Date published: 2017-11-02
Rated 4 out of 5 by from good antibodyNPY antibody is worked well in WB detection in rat ovarian tissue
Date published: 2017-10-25
Rated 5 out of 5 by from Recommended useNPY antibody had powerful band detected of cell lines, it provides clear and specific results.So we decide to buy it continue.
Date published: 2017-10-17
Rated 5 out of 5 by from works wellIt works well in western blotting at dilution of 1:500 analysis Human liver tissue .
Date published: 2017-02-12
Rated 1 out of 5 by from Ne fonctionne pas chez la sourisNe fonctionne ni en WB sur des extraits de testicules de souris ni en immunohistochimie sur des testicules de souris
Date published: 2017-02-02
Rated 5 out of 5 by from Good antibodyUse the antibodies in western blotting and get the correct band 1:100 dilution.
Date published: 2017-01-16
Rated 4 out of 5 by from Nice WB data obtained using human recombinantNice WB data obtained using human recombinant NPY precursor fusion protein and human recombinant NPY fusion protein incubated with active NPY. -SCBT QC
Date published: 2015-02-03
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_zh_CN, sid_133080, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
NPY 抗体 (F-6) is rated 4.3 out of 5 by 9.
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_zh_CN, sid_133080, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 80ms
  • REVIEWS, PRODUCT