Date published: 2025-9-10

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Nix 抗体 (E-1): sc-166314

5.0(4)
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说明书
  • Nix抗体(E-1)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Nix的N-terminus附近的氨基酸19-47之间
  • 推荐用于 mouse, rat 和 human 来源的Nix WB, IP, IF, IHC(P) 和 ELISA检测
  • 目前,我们还没有完成Nix 抗体 (E-1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

腺病毒E1B蛋白是参与调节细胞死亡的Bcl-2蛋白家族的病毒同源物。被指定为Nip或Bnip的一系列相互作用蛋白,包括Nip1、Nip2、Nip3和Nix,与E1B蛋白和Bcl-2蛋白结合以介导凋亡信号传导。Nip1包含一个疏水跨膜结构域,使其能够定位于核膜、内质网和线粒体。Nip2与Cdc42 GTPase激活蛋白(Cdc42GAP)的非催化结构域具有同源性。通过与Cdc42GAP结合,Nip2增强了Cdc42GAP的GTPase活性,促进了与Cdc42结合的GTP的水解,从而介导了涉及受体激酶、小GTP酶和凋亡蛋白的信号通路。被指定为Nip3L或Bnip3L的Nix与Nip3高度相关,并且这两种蛋白都定位于线粒体,在那里它们与Bcl-2蛋白结合。Nip3优先与Bcl-xL结合,并通过抑制Bcl-xL的抗凋亡活性来诱导凋亡。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Nix 抗体 (E-1)

sc-166314
200 µg/ml
$316.00

Nix (E-1) 中和勝肽

sc-166314 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-166314 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Works well in WBBy western blotting a specific cell, is clear and specific
Date published: 2017-05-10
Rated 5 out of 5 by from Perfect monoclonal antibodiesI found that Western Blotting can usually be diluted with 1:500 and got a very nice signal
Date published: 2017-04-11
Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date published: 2015-01-05
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Nix 抗体 (E-1) is rated 5.0 out of 5 by 4.
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