m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for MRE11 Antibody (18) for WB applications. These reagents are now offered in bundles with MRE11 Antibody (18) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MRE11 Antibody (18) is a high quality monoclonal MRE11 antibody (also designated Double Strand Break Repair Nuclease antibody, Double-Strand Break Repair Protein MRE11A antibody, Double-Strand Break Repair Protein MRE11 antibody, Meiotic Recombination 11 Homolog 1 antibody, Meiotic Recombination 11 Homolog antibody, AT-Like Disease antibody, MRE11 Homolog 1 antibody, MRE11A antibody, HNGS1 antibody, ATLD antibody, Meiotic Recombination 11-Like Protein A antibody, MRE11 Double Strand Break Repair Nuclease A antibody, DNA Recombination And Repair Protein antibody, or Endonuclease Exonuclease antibody) suitable for the detection of the MRE11 protein of mouse, rat and human origin. MRE11 Antibody (18) is available as the non-conjugated anti-MRE11 antibody. Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54 and MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that could otherwise cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. MRE11 (meiotic recombination 11, ATLD, HNGS1) is a nuclear 3′ -5′ exonuclease/endonuclease that associates with RAD50 and influences homologous recombination, telomere length maintenance, and DNA double-strand break repair. MRE11 is most abundant in proliferating tissues.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.