m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for MOV10 Antibody (B-3) for WB applications. This reagent is now offered in a bundle with MOV10 Antibody (B-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Labware ships FedEx Ground free of charge to the contiguous US
MOV10 Antibody (B-3) is a high quality monoclonal MOV10 antibody (also designated MOV10 antibody) suitable for the detection of the MOV10 protein of mouse, rat and human origin. MOV10 Antibody (B-3) is available as both the non-conjugated anti-MOV10 antibody form, as well as multiple conjugated forms of anti-MOV10 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. MOV10 (Moloney leukemia virus 10), also known as putative helicase MOV-10, gb110 or fSAP113, is a 1,003 amino acid novel telomerase-associated protein that belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. Localizing to mRNA-degrading cytoplasmic P bodies, MOV10 may function as a RNA helicase that is required to mediate miRNA-guided mRNA cleavage and RNA-mediated gene silencing by the RISC (RNA-induced silencing) complex. Highly expressed in ovary and testis, MOV10 is involved in hepatitis delta virus (HDV) transcription and replication, and is known to interact with eIF2C1, eIF2C2, eIF6, Dicer and TRBP2. MOV10 exists as three alternatively spliced isoforms that are encoded by a gene located on human chromosome 1 and mouse chromosome 3. Following translation, MOV10 may become phosphorylated upon DNA damage by either ATM or ATR.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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