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Measles H 抗体 (6017): sc-517542

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说明书
  • Measles H 抗体 6017 是小鼠单克隆 IgG2b，Measles H抗体，规格为100 µg/ml
  • 培养自麻疹病毒来源的Edmonston菌株
  • 推荐用于 Measles hemagglutinin IF 和 ELISA检测
  • 目前，我们还没有完成Measles H 抗体 (6017)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    描述
    说明书与实验方案

    関連項目

    此外 Measles virus 抗体包括 Measles H, Measles M 和 Measles NP

    麻疹H抗体（6017）是一种小鼠单克隆IgG2b抗体，可通过免疫荧光（IF）和酶联免疫吸附测定（ELISA）检测人类和猴类的麻疹H蛋白。抗麻疹H抗体（6017）以非结合形式提供，专门针对麻疹病毒的糖蛋白血凝素，这是一种高度传染性的副粘病毒，可导致严重的呼吸道疾病。麻疹H蛋白在病毒附着和宿主细胞进入方面起着关键作用，有助于感染和随后的病毒复制。麻疹H蛋白与细胞受体相互作用，这是病毒致病性的关键，使病毒能够逃避宿主免疫反应并建立感染。了解麻疹H蛋白的功能对于开发有效的疫苗和治疗策略来对抗麻疹至关重要，特别是考虑到这种可预防的疾病在各个地区卷土重来。麻疹病毒以引发肺炎和脑炎等严重并发症而闻名，它通过血凝素蛋白来传播，因此麻疹H蛋白成为研究和临床诊断的重要目标。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Measles H 参考文献:

    1. 发展中国家的麻疹。  |  Halsey, NA. 2006. BMJ. 333: 1234. PMID: 17170396
    2. 麻疹补充免疫活动提高了麻疹疫苗的覆盖率和公平性：来自肯尼亚的证据，2002 年。  |  Vijayaraghavan, M., et al. 2007. Health Policy. 83: 27-36. PMID: 17174435
    3. 麻疹--美国，2005 年。  |  ,. 2006. MMWR Morb Mortal Wkly Rep. 55: 1348-51. PMID: 17183226
    4. 麻疹在未接种疫苗的人群中仍具有破坏性影响。  |  Moss, WJ. 2007. PLoS Med. 4: e24. PMID: 17199409
    5. 麻疹病毒核苷酸转运到质膜需要病毒基质蛋白的稳定表达和表面积累。  |  Runkler, N., et al. 2007. Cell Microbiol. 9: 1203-14. PMID: 17217427
    6. 基质蛋白与血凝素胞质尾相互作用的改变通过影响病毒组装和细胞-细胞融合来调节麻疹病毒的生长。  |  Tahara, M., et al. 2007. J Virol. 81: 6827-36. PMID: 17442724
    7. 用单克隆抗体鉴定麻疹病毒的主要结构蛋白。  |  Sato, TA., et al. 1985. J Gen Virol. 66 (Pt 7): 1397-409. PMID: 2410551
    8. 针对麻疹病毒五种结构成分的单克隆抗体。I. 九株麻疹病毒抗原决定簇的特征。  |  Sheshberadaran, H., et al. 1983. Virology. 128: 341-53. PMID: 6193632
    9. 麻疹病毒基因型的时间和地理分布。  |  Rima, BK., et al. 1995. J Gen Virol. 76 (Pt 5): 1173-80. PMID: 7730801

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Measles H 抗体 (6017)

    sc-517542
    100 µg/ml
    		$316.00

    Hi there, do you recommend to use these antibodies for the wester blot? thanks

    Asked by: Eltor
    Thank you for your question. Anti-Measles H Antibody (6017): sc-517542 is only recommended for detection of measles hemagglutinin by IF ELISA. We do not recommend it for western blots.
    Answered by: Tech Support Europe
    Date published: 2023-01-18

    Where in the H-antigen is the epitope of this antibody located ?

    Asked by: Sigurd
    Thank you for your question. Measles H Antibody (6017): sc-517542 has been raised against the Edmonston strain of Measles virus origin. The exact epitope of this antibody has not yet been determined, so the binding site of the antibody on its target protein is not known.
    Answered by: Tech Support Europe
    Date published: 2019-07-08
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    Rated 1 out of 5 by from It does not work for ELISA eitherI had issues with detecting my protein. it does not work and causes background! not happy with this antibody and expected better products from Santa Cruz. I used it for IF ELISA and Westernblot ! used other antibodies to compare and for sure this antibody did not work!
    Date published: 2023-01-18
    Rated 1 out of 5 by from Bad antibodyI bought this a few weeks back. This antibody does not work. It binds to non-specific antigens giving a very high background in immunofluorescence.
    Date published: 2019-10-01
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    Measles H 抗体 (6017) is rated 1.0 out of 5 by 2.
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