Lymphocyte Marker Antibody (MB3): sc-52340

Lymphocyte Marker Antibody (MB3) is a mouse monoclonal IgG2b antibody that detects Lymphocyte Marker (MB3) of human origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Lymphocyte Marker (MB3) antibody is available in a non-conjugated form, providing flexibility for various experimental needs. Lymphocytes, a crucial component of the immune system, are primarily located in the blood and lymphatic tissues, where they play a vital role in immune responses. The two main types of lymphocytes, T cells and B cells, are essential for adaptive immunity; T cells are involved in cell-mediated immunity, while B cells are responsible for producing antibodies in response to antigens. The localization of lymphocytes in lymphoid organs, such as the spleen and lymph nodes, is critical for their function, as this allows for efficient interaction with antigens and other immune cells. This strategic positioning facilitates the rapid activation and proliferation of lymphocytes upon encountering pathogens, ensuring a swift and effective immune response. Lymphocyte Marker monoclonal antibody (MB3) enables researchers to identify and study these vital immune cells, contributing to a deeper understanding of immune mechanisms and potential therapeutic targets.

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Lymphocyte Marker Antibody (MB3) References:

1. An immature rat lymphocyte marker CD157: striking differences in the expression between mice and rats.  |  Seki, M., et al. 2001. Immunobiology. 203: 725-42. PMID: 11563673
2. Monoclonal antibody BA-1 to the human B lymphocyte marker CD24 recognizes a sialic acid (N-acetylneuraminic acid) dependent epitope in multi-valent display on peptide.  |  Mehmet, H., et al. 1990. Clin Exp Immunol. 81: 489-95. PMID: 1697799
3. The human intraepithelial lymphocyte marker HML-1 is an integrin consisting of a beta 7 subunit associated with a distinctive alpha chain.  |  Cerf-Bensussan, N., et al. 1992. Eur J Immunol. 22: 273-7. PMID: 1730254
4. STB1, a mouse lymphocyte marker found on T cell and B cell subpopulations.  |  Andrew, D. and Jayakumar, J. 1990. Cell Immunol. 126: 16-30. PMID: 2105852
5. The clinical relevance of lymphocyte marker studies in the diagnosis of lymphoma.  |  Harris, NL. 1989. Keio J Med. 38: 152-66. PMID: 2674515
6. Human sessile B lymphocyte marker defined by a monoclonal antibody.  |  Forster, HK., et al. 1982. Adv Exp Med Biol. 149: 61-5. PMID: 6293283
7. Lymphocyte marker testing in relation to the clinical use of dialyzed leukocyte extract containing transfer factor (DLE-LTF).  |  Peetoom, F. and Florey, MJ. 1980. Haematologia (Budap). 13: 225-37. PMID: 7250812
8. Monoclonal antibodies to the equine CD2 T lymphocyte marker, to a pan-granulocyte/monocyte marker and to a unique pan-B lymphocyte marker.  |  Tumas, DB., et al. 1994. Immunobiology. 192: 48-64. PMID: 7750989
9. The construction and characterization of poliovirus antigen chimeras presenting defined regions of the human T lymphocyte marker CD4.  |  Rose, C., et al. 1994. J Gen Virol. 75 (Pt 5): 969-77. PMID: 8176383