lactoferrin Antibody (1A1): sc-52048
- lactoferrin Antibody (1A1) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against purified lactoferrin from human milk
- recommended for detection of lactoferrin of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for lactoferrin Antibody (1A1). This work is in progress.
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SEE ALSO...
Lactoferrin Antibody (1A1) is a mouse monoclonal IgG1 antibody that detects lactoferrin in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Anti-lactoferrin antibody (1A1) binds to lactoferrin, which plays a crucial role in iron metabolism by binding to iron and regulating its availability in biological systems, essential for various cellular processes, including immune response and cellular proliferation. Lactoferrin is primarily located in secretory fluids such as milk, tears, and leukocytes, where lactoferrin not only serves as an iron transporter but also exhibits antimicrobial properties, helping to protect against infections. Lactoferrin′s ability to bind iron limits its availability to pathogens, thereby inhibiting their growth. Additionally, lactoferrin has been shown to modulate immune responses, influencing the activation and proliferation of lymphocytes, which is vital for maintaining a balanced immune system. The gene encoding human lactoferrin is located on chromosome 3p21.31, highlighting lactoferrin′s significance in human health and disease. With multifaceted roles in iron regulation and immune modulation, lactoferrin is a key protein for researchers studying iron metabolism and host-pathogen interactions.
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lactoferrin Antibody (1A1) References:
- Lactoferrin and necrotizing enterocolitis. | Sherman, MP., et al. 2014. Curr Opin Pediatr. 26: 146-50. PMID: 24503532
- Immunomodulatory effects of lactoferrin. | Siqueiros-Cendón, T., et al. 2014. Acta Pharmacol Sin. 35: 557-66. PMID: 24786230
- Studying Lactoferrin N-Glycosylation. | Karav, S., et al. 2017. Int J Mol Sci. 18: PMID: 28425960
- Lactoferrin: Structure, function, denaturation and digestion. | Wang, B., et al. 2019. Crit Rev Food Sci Nutr. 59: 580-596. PMID: 28933602
- Lactoferrin in Bone Tissue Regeneration. | Icriverzi, M., et al. 2020. Curr Med Chem. 27: 838-853. PMID: 31258057
- The N-glycans of lactoferrin: more than just a sweet decoration. | Zlatina, K. and Galuska, SP. 2021. Biochem Cell Biol. 99: 117-127. PMID: 32464076
- The role of lactoferrin in atherosclerosis. | Chen, C., et al. 2023. Biometals. 36: 509-519. PMID: 36053470
- Lactoferrin-Conjugated Nanoparticles as New Antivirals. | Krzyzowska, M., et al. 2022. Pharmaceutics. 14: PMID: 36145610
- The Role of Lactoferrin in Intestinal Health. | Conesa, C., et al. 2023. Pharmaceutics. 15: PMID: 37376017
- Lactoferrin, the Moonlighting Protein of Innate Immunity. | Cutone, A., et al. 2023. Int J Mol Sci. 24: PMID: 37958871
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
lactoferrin Antibody (1A1) | sc-52048 | 100 µg/ml | $322.00 |