Ketorolac (CAS 74103-06-3)

外观 :

Crystalline powder

物理状态 :

Solid

溶解度 :

Soluble in water (partly), and ethanol (~1 mg/ml).

保存 :

Store at room temperature

熔点 :

160.5° C

沸点 :

223.7° C at 760 mmHg

密度 :

~1.3 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.66 (Predicted)

IC50 :

COX-1: IC₅₀ = 13 nM (human); COX-2: IC₅₀ = 120 nM (human); Prostaglandin-H2 D-isomerase: IC₅₀ = 230 nM (mouse); Aldose reductase: IC₅₀ = 6.11 µM (rat)

Ki 数据 :

Fatty acid-binding protein, liver: K_i= 11.6 µM (rat)

pK值 :

pK_a: 3.49

RTECS :

UY7759800

运输 :

UN 3249, Class 6.1, Packing group II

PubChem CID :

Merck 索引 :

14: 5306

MDL 号码 :

MFCD00864281

EC号码 :

616-049-1

SMILES :

C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O