Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

Inhibin β-A 抗体 (E-1): sc-166503

5.0(5)
寫評論提問

说明书
  • Inhibin beta-A 抗体 E-1 是小鼠单克隆 IgG2a κ,Inhibin β-A抗体, 在11篇文献中引用,规格为200 µg/ml
  • 特定用于氨基酸307-426之间的表位图谱绘制,在C-terminus的Inhibin β-A的human原点处绘制
  • Inhibin beta-A 抗体 (E-1) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 precursor and mature Inhibin β-A; 也和以下物种反应,包括: 和 bovine and porcine
  • 抗Inhibin beta-A抗体(E-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Inhibin β-A (E-1): sc-166503免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Inhibin β-A Antibody (E-1) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Inhibin β-A Antibody (E-1) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

Inhibin β-A 抗体(E-1)是一种 IgG2a κ 小鼠单克隆 Inhibin beta-A 抗体(也称为 Inhibin 亚基 Beta A 抗体、红细胞分化蛋白抗体、Inhibin Beta A 链抗体、Activin Beta-A 链抗体、EDF 抗体、卵泡刺激素释放蛋白抗体、红细胞分化因子抗体、Inhibin Beta A 亚基抗体、FSH 释放蛋白抗体、Inhibin Beta A 抗体、Inhibin Beta-1 抗体或 FRP 抗体),可通过蛋白质印迹、免疫沉淀、免疫荧光和酶联免疫吸附试验检测小鼠、大鼠和人类来源的 Inhibin beta-A 蛋白。Inhibin β-A 抗体(E-1)既以非偶联的抗 Inhibin beta-A 抗体形式提供,也以多种偶联形式的抗 Inhibin beta-A 抗体提供,包括琼脂糖、HRP、PE、FITC 和多种 Alexa Fluor® 偶联物。TGFβ 超家族由众多生长和分化因子组成,包括转化生长因子 β(TGFβ)1、2 和 3;生长/分化因子(GDF)1 至 8;Mullerian 抑制物质(MIS);骨形态发生蛋白(BMP)2 至 8;胶质细胞源性神经营养因子(GDNF);抑制素(α、β-A、β-B 和 β-C)、Lefty 和 Nodal。TGFβ 超家族的成员参与胚胎发育和成人组织稳态的维持。抑制素和激活素分别抑制和激活垂体腺分泌促卵泡激素。抑制素和激活素根据其亚基组成参与调节多种功能,如下丘脑和垂体激素分泌、性腺激素分泌、生殖细胞发育和成熟、红细胞分化、胰岛素分泌、神经细胞存活、胚胎轴向发育或骨骼生长。激活素与抑制素的功能相反。抑制素主要在肝脏、子宫和卵巢组织中表达。抑制素 A 是 α 和 β-A 的二聚体,抑制素 B 是 α 和 β-B 的二聚体,已知可抑制卵泡刺激素的分泌。Inhibin β-C 形成同源二聚体,其主要在成人肝脏中表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Inhibin β-A 抗体 (E-1) 参考文献:

  1. 转化生长因子-β 家族。  |  Massagué, J. 1990. Annu Rev Cell Biol. 6: 597-641. PMID: 2177343
  2. 多种乙型转化生长因子及其受体。  |  Massagué, J., et al. 1987. J Cell Physiol Suppl. Suppl 5: 43-7. PMID: 2890647
  3. 来自猪卵巢和人类胎盘的抑制素 A 亚基 cDNAs。  |  Mayo, KE., et al. 1986. Proc Natl Acad Sci U S A. 83: 5849-53. PMID: 3016724
  4. 抑制素βA通过调节转化生长因子-β通路,促进大肠癌的恶性生物学行为。  |  He, Z., et al. 2021. Cell Biochem Funct. 39: 258-266. PMID: 32662905
  5. 抑制素βA(INHBA)通过激活TGF-β信号通路诱导上皮-间质转化并加速乳腺癌细胞的移动。  |  Yu, Y., et al. 2021. Bioengineered. 12: 4681-4696. PMID: 34346300
  6. 丹参酮 I 通过下调抑制素 beta-A 减轻纤维化肾脏的纤维化。  |  Wu, M., et al. 2022. BMC Complement Med Ther. 22: 110. PMID: 35439976
  7. 随着年龄的增长,人类表皮抑制素βA/激活素-A表达增加,表皮干细胞/祖细胞增殖受到抑制。  |  Kawagishi-Hotta, M., et al. 2022. J Dermatol Sci. 106: 150-158. PMID: 35610160
  8. 激活素亚基抑制素βA对胃癌和食管腺癌的预后影响。  |  Staudacher, JJ., et al. 2022. BMC Cancer. 22: 953. PMID: 36064338
  9. 人类抑制素基因。基因组特征和测序  |  Stewart, AG., et al. 1986. FEBS Lett. 206: 329-34. PMID: 3758355
  10. 激活蛋白在胚胎植入前的小鼠胚胎以及 ES 和 EC 细胞中都有表达,并在其分化过程中受到调控。  |  Albano, RM., et al. 1993. Development. 117: 711-23. PMID: 8330535
  11. 小鼠抑制素/活化素 beta C(Inhbc)基因的结构, 染色体定域和表达分析。  |  Schmitt, J., et al. 1996. Genomics. 32: 358-66. PMID: 8838799
  12. 一种新的 TGF-beta 超家族成员对小鼠骨骼肌质量的调节。  |  McPherron, AC., et al. 1997. Nature. 387: 83-90. PMID: 9139826

订购信息

产品名称产品编号规格价格数量收藏夹

Inhibin β-A 抗体 (E-1)

sc-166503
200 µg/ml
$316.00

Inhibin β-A (E-1): m-IgG Fc BP-HRP 套装

sc-528982
200 µg Ab; 10 µg BP
$354.00

Inhibin β-A (E-1): m-IgGκ BP-HRP 套装

sc-521634
200 µg Ab, 40 µg BP
$354.00

Inhibin β-A (E-1): m-IgG2a BP-HRP 套装

sc-547224
200 µg Ab; 10 µg BP
$354.00

Inhibin β-A 抗体 (E-1) AC

sc-166503 AC
500 µg/ml, 25% agarose
$416.00

Inhibin β-A 抗体 (E-1) HRP

sc-166503 HRP
200 µg/ml
$316.00

Inhibin β-A 抗体 (E-1) FITC

sc-166503 FITC
200 µg/ml
$330.00

Inhibin β-A 抗体 (E-1) PE

sc-166503 PE
200 µg/ml
$343.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 488

sc-166503 AF488
200 µg/ml
$357.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 546

sc-166503 AF546
200 µg/ml
$357.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 594

sc-166503 AF594
200 µg/ml
$357.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 647

sc-166503 AF647
200 µg/ml
$357.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 680

sc-166503 AF680
200 µg/ml
$357.00

Inhibin β-A 抗体 (E-1) Alexa Fluor® 790

sc-166503 AF790
200 µg/ml
$357.00

Dose this antibody work for IF on 4% PFA fixed mouse brain frozen sections? Thanks!

Asked by: Cathy
Thank you for your question. sc-166503 Inhibin β-A (E-1) can be used for IF in PFA fixed mouse samples.
Answered by: BlakeJ
Date published: 2025-03-27

What dilution is recommended for Western Blot when using cell line lysates?

Asked by: RM13
Thank you for your question. Inhibin b-A (E-1) is recommended for detection of precursor and mature Inhibin b-A of mouse, rat and human origin by Western Blotting (starting dilution 1:100, dilution range 1:100-1:1000)
Answered by: Tech Support Europe
Date published: 2022-11-18

Is the exact epitope sequence known, or is the antibody raised against the whole 307-426 peptide? This information is needed in order to know whether it would recognize a modified, shortened mature domain or not.

Asked by: Frakper
Thank you for your question. This antibody was raised against a recombinant protein corresponding to amino acids 307-426. The exact epitope recognized by this mouse monoclonal antibody has not yet been determined.
Answered by: Technical Support
Date published: 2019-08-17

What is the recommended secondary reagent for Western blot applications if I am working with human tissue samples?

Asked by: Trav11
Thank you for your question. We recommend using one of our exclusive Mouse IgG Binding Proteins as a secondary detection reagent, such as m-IgGκ BP-HRP: sc-516102, for Western blot. A complete list of all available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-8301 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Technical Support 9
Date published: 2017-01-16

Why is Inhibin β-A Antibody (E-1): sc-166503 the recommended alternative to the now discontinued Inhibin β-A (H-120): sc-50288?

Asked by: Trav11
Thank you for your question. The mouse monoclonal Inhibin β-A Antibody (E-1): sc-166503 is raised against the same immunogen sequence as the rabbit polyclonal Inhibin β-A (H-120): sc-50288. The monoclonal primary antibody also offers a higher degree of specificity and eliminates lot-to-lot variation. It is also warrantied for all of the same applications as the discontinued polyclonal antibody: WB, IP, IF, and ELISA. If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Technical Support 8
Date published: 2017-01-16
  • y_2025, m_8, d_27, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_5
  • loc_zh_CN, sid_166503, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 110ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from 不错的我之前买了这个产品,确实还不错,希望下一次和他们再合作,冲冲冲,嘎嘎嘎嘎阿嘎嘎嘎,,,,,,,,,,,
Date published: 2024-04-09
Rated 5 out of 5 by from Great antibodyStrong western blot data; specific with low background
Date published: 2017-01-14
Rated 5 out of 5 by from Works well in WBDoes a good job detecting Inhibin beta-A in transfected whole cell lysates in WB.
Date published: 2016-12-22
Rated 5 out of 5 by from Produced positive Western Blot data of InhibinProduced positive Western Blot data of Inhibin -A expression in non-transfected and mouse Inhibin -A transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-02-24
Rated 5 out of 5 by from Nice Western Blot data of InhibinNice Western Blot data of Inhibin -A expression in non-transfected and human Inhibin -A transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-04-28
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_166503, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
Inhibin β-A 抗体 (E-1) is rated 5.0 out of 5 by 5.
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_166503, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 109ms
  • REVIEWS, PRODUCT