Date published: 2025-9-8
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Influenza A m1 抗体 (FluAc): sc-69824

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说明书
  • Influenza A m1 抗体 FluAc 是小鼠单克隆 IgG2b κ，Influenza A m1抗体, 在11篇文献中引用，规格为100 µg/ml
  • 针对重组Influenza A m1
  • 推荐用于 Influenza A Virus 来源的Influenza A m1 WB 和 IF检测
  • 关于如何获取Influenza A m1 (FluAc): sc-69824的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前，我们还没有完成Influenza A m1 抗体 (FluAc)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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描述
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研究信息

関連項目

此外 Influenza 抗体 包括 Influenza A m1, Influenza A m2, Influenza A NP, Influenza A ns1, Influenza A Virus Hemagglutinin, Influenza B, Influenza B M1, Influenza B NA和Influenza B NP

甲型流感 m1 抗体（FluAc）是一种小鼠单克隆 IgG2b kappa 轻链抗体，可通过免疫印迹（WB）和免疫荧光（IF）检测甲型流感病毒来源的甲型流感 m1 蛋白。抗甲型流感 m1 抗体（FluAc）为非结合型。甲型流感 m1 蛋白在病毒生命周期中发挥着关键作用，尤其是在病毒的组装和出芽过程中。甲型流感 m1 蛋白位于病毒包膜中，并在这些阶段保持结构的完整性。甲型流感 m1 蛋白与血凝素（HA）和神经氨酸酶（NA）等其他病毒蛋白相互作用，这些蛋白对病毒感染宿主细胞的能力至关重要。HA 通过胞质尾部和跨膜结构域与甲型流感 m1 蛋白结合，促进病毒包膜的正常组装。了解甲型流感 m1 蛋白的功能和位置对于制定抗病毒策略非常重要，因为针对这种蛋白的抗病毒策略可以破坏病毒的复制和传播。流感病毒分为甲、乙、丙三型，其中甲型和乙型是呼吸道疾病季节性流行的罪魁祸首。使用抗甲型流感 m1 抗体（FluAc）检测和研究甲型流感 m1 蛋白对于研究抗击流感爆发和改善公共卫生应对措施至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Influenza A m1 抗体 (FluAc) 参考文献:

  1. 基于实验的膜蛋白模型定向细化：甲型流感 M2 H+ 通道的结构。  |  Kukol, A., et al. 1999. J Mol Biol. 286: 951-62. PMID: 10024461
  2. 甲型流感病毒 M（2）离子通道的质子传导机制。  |  Mould, JA., et al. 2000. J Biol Chem. 275: 8592-9. PMID: 10722698
  3. 流感病毒组装：流感病毒糖蛋白对 M1 蛋白膜缔合作用的影响。  |  Ali, A., et al. 2000. J Virol. 74: 8709-19. PMID: 10954572
  4. 表达显性和亚显性 TCR 的甲型流感特异性细胞毒性 T 淋巴细胞克隆之间的功能差异。  |  Lawson, TM., et al. 2001. Int Immunol. 13: 1383-90. PMID: 11675370
  5. 流感和其他病毒性肺炎的最新情况。  |  Fleming, DM. and Zambon, M. 2001. Curr Opin Infect Dis. 14: 199-204. PMID: 11979133
  6. 确定 Hsc70 是参与病毒生命周期的流感病毒基质蛋白（M1）结合因子。  |  Watanabe, K., et al. 2006. FEBS Lett. 580: 5785-90. PMID: 17022977
  7. 甲型流感 M1 mRNA 内含子中保守结构域的二级结构。  |  Jiang, T., et al. 2014. Biochemistry. 53: 5236-48. PMID: 25026548
  8. 急性传染性单核细胞增多症的严重程度与交叉反应性流感 CD8 T 细胞受体反应相关。  |  Aslan, N., et al. 2017. mBio. 8: PMID: 29208744
  9. 从甲型流感病毒 M1 蛋白中提取的含两性 CRAC 的肽可调节培养的 IC-21 巨噬细胞的胆固醇依赖性活性。  |  Dunina-Barkovskaya, AY., et al. 2018. Biochemistry (Mosc). 83: 982-991. PMID: 30208834
  10. 用于病毒性疾病治疗药物开发的蛋白质折叠阻断策略：埃博拉病毒 VP40 和甲型流感 M1。  |  Bergasa-Caceres, F. and Rabitz, HA. 2022. Int J Mol Sci. 23: PMID: 35409264
  11. 交叉反应在甲型流感 M158-66 变异肽表位的细胞免疫靶向中的作用。  |  Petrova, GV., et al. 2022. Front Immunol. 13: 956103. PMID: 36211433
  12. 甲型流感病毒 M2 质子通道的功能定义模型表明了其离子选择性的机制。  |  Pinto, LH., et al. 1997. Proc Natl Acad Sci U S A. 94: 11301-6. PMID: 9326604

订购信息

产品名称产品编号规格价格数量收藏夹

Influenza A m1 抗体 (FluAc)

sc-69824
100 µg/ml
$316.00

Do this antibody can recognition M1 protein of pandemic strain?

Asked by: Fer24
Thank you for your question. This monoclonal FluAc antibody specifically recognizes type A influenza virus M1 in virus infected cell culture. We do not have information regarding pandemic strain reactivity.
Answered by: Technical Support
Date published: 2019-06-16

Do you sell any positive controls for use with this Influenza A m1 (FluAc): sc-69824 monoclonal antibody?

Asked by: cjMara
No, we do not offer any positive controls for use with any of our Influenza A m1 antibodies. We would recommend referring to some of the product citations on our website as a reference to see how other researchers are using this antibody in their research.
Answered by: Technical Support 6
Date published: 2017-01-20
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Rated 1 out of 5 by from Didn't work in our hands in IF with MDCK cellsThe antibody gave no signal in IF with MDCK cells infected by Influenza A PR8, whereas 3 other antibodies from Santa Cruz worked well.
Date published: 2022-08-24
Rated 5 out of 5 by from dataClean and clear blot with this antibody for WB(1/200 dilution) analysis
Date published: 2017-05-14
Rated 5 out of 5 by from Solid antibody!Reliable and strong antibody for detection of Influenza A m1.
Date published: 2017-01-09
Rated 5 out of 5 by from Produced publishable data with dog MadinProduced publishable data with dog Madin-Darby canine kidney and human alveolar epithelial cell (A549) and 293T cells - SCBT Publication Review
Date published: 2015-04-20
Rated 5 out of 5 by from This antibody worked well for WB with humanThis antibody worked well for WB with human lung epithelial cells(A549) - SCBT Publication Review
Date published: 2015-03-23
Rated 5 out of 5 by from Used in IPUsed in IP, WB with human A549 and 293T cells - SCBT Publication Review
Date published: 2014-04-06
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Influenza A m1 抗体 (FluAc) is rated 4.3 out of 5 by 6.
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