Date published: 2025-9-7

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IL-13 抗体 (F-6): sc-390676

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说明书
  • IL-13抗体(F-6)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 与human的104-132氨基酸残基的IL-13
  • IL-13 抗体 (F-6) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 IL-13
  • 抗IL-13抗体(F-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IL-13 (F-6): sc-390676免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是IL-13 Antibody (F-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与IL-13 Antibody (F-6) 打包提供(请参阅下面的订购信息)。

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関連項目

IL-13抗体(F-6)是一种IgG1 κ小鼠单克隆IL-13抗体,可通过WB、IP、IF和ELISA检测人源IL-13。IL-13抗体(F-6)既可作为非偶联形式的抗IL-13抗体,也可作为多种偶联形式的抗IL-13抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。白细胞介素-13(IL-13)是一种多效性细胞因子,与IL-4具有30%的序列同一性,并具有许多相同的生物学活性。与IL-4一样,IL-13通过上调CD23和MHC蛋白的表达以及下调CD14的表达来影响单核细胞、巨噬细胞和B细胞。IL-4和IL-13都由活化的T淋巴细胞分泌,是炎症的有力调节剂。两者都能抑制活化的单核细胞中促炎细胞因子和化学因子的分泌,并刺激活化的B细胞上IgE的表达。IL-13含有五个半胱氨酸残基和多个N-连接糖基化位点,据报道可抑制自然杀伤细胞中IL-2的产生。IL-13 cDNA编码一个由131个氨基酸组成的前体,该前体具有一个20个氨基酸的信号肽,该信号肽被切割以产生成熟蛋白质。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IL-13 抗体 (F-6) 参考文献:

  1. IL-13的信号转导及其在支气管哮喘发病机理中的作用。  |  Izuhara, K. and Arima, K. 2004. Drug News Perspect. 17: 91-8. PMID: 15098062
  2. 肺纤维化中IL-4和IL-13反应性细胞的治疗靶向。  |  Jakubzick, C., et al. 2004. Immunol Res. 30: 339-49. PMID: 15531774
  3. IL-4和IL-13双重拮抗:一种有望解决有效哮喘生物治疗难题的方法。  |  Borish, L. 2010. Am J Respir Crit Care Med. 181: 769-70. PMID: 20382798
  4. IL-4/IL-13通路基因的多态性与胶质瘤风险:更新的荟萃分析。  |  Chen, P., et al. 2015. Tumour Biol. 36: 121-7. PMID: 25472582
  5. IL-13对牙周炎中TGF-β和MMP-1的影响。  |  Beklen, A. 2017. Biotech Histochem. 92: 374-380. PMID: 28682139
  6. IL-13受体作为弥漫性桥脑胶质瘤的可能治疗靶点。  |  Berlow, NE., et al. 2018. PLoS One. 13: e0193565. PMID: 29621254
  7. IL-4和IL-13在皮肤过敏中的常见和不同作用及其临床意义。  |  Roesner, LM., et al. 2019. Curr Opin Allergy Clin Immunol. 19: 319-327. PMID: 31157635
  8. 划痕通过上调角质形成细胞中的诱饵受体 IL-13Rα2 来抵消 IL-13 信号传导  |  Ulzii, D., et al. 2019. Int J Mol Sci. 20: PMID: 31284553
  9. IL-4/IL-13 上调音速刺猬表达,诱导过敏性气道上皮重塑。  |  Wang, X., et al. 2020. Am J Physiol Lung Cell Mol Physiol. 318: L888-L899. PMID: 32130032
  10. IL-13作为减少Abcb4基因敲除小鼠胆汁淤积和营养不良的目标。  |  Hahn, L., et al. 2020. Cells. 9: PMID: 32846954

订购信息

产品名称产品编号规格价格数量收藏夹

IL-13 抗体 (F-6)

sc-390676
200 µg/ml
$316.00

IL-13 (F-6): m-IgGκ BP-HRP 套装

sc-523632
200 µg Ab, 40 µg BP
$354.00

IL-13 (F-6): m-IgG1 BP-HRP 套装

sc-533600
200 µg Ab; 20 µg BP
$354.00

IL-13 抗体 (F-6) AC

sc-390676 AC
500 µg/ml, 25% agarose
$416.00

IL-13 抗体 (F-6) HRP

sc-390676 HRP
200 µg/ml
$316.00

IL-13 抗体 (F-6) FITC

sc-390676 FITC
200 µg/ml
$330.00

IL-13 抗体 (F-6) PE

sc-390676 PE
200 µg/ml
$343.00

IL-13 抗体 (F-6) Alexa Fluor® 488

sc-390676 AF488
200 µg/ml
$357.00

IL-13 抗体 (F-6) Alexa Fluor® 546

sc-390676 AF546
200 µg/ml
$357.00

IL-13 抗体 (F-6) Alexa Fluor® 594

sc-390676 AF594
200 µg/ml
$357.00

IL-13 抗体 (F-6) Alexa Fluor® 647

sc-390676 AF647
200 µg/ml
$357.00

IL-13 抗体 (F-6) Alexa Fluor® 680

sc-390676 AF680
200 µg/ml
$357.00

IL-13 抗体 (F-6) Alexa Fluor® 790

sc-390676 AF790
200 µg/ml
$357.00

IL-13 (F-6) 中和勝肽

sc-390676 P
100 µg/0.5 ml
$68.00

Hello,, I ordered this antibody and received it two weeks ago. Unfortunately the person received the order stored the Ab at -20 for two weeks now and once I am in today I moved that to 4 degree fridge. Will the freezing impact my experiments?

Asked by: Khadija
Thank you for your question. I am sorry to hear that this has happened, and yes in most cases freezing a normal antibody will likely impact its effectiveness. Feel free to contact us to order a replacement. -Tech Service
Answered by: Tech Service 1
Date published: 2021-02-04

What application is the blocking peptide sc-390676 P appropriate for?

Asked by: DefinitelyNotMatt
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Uses antibody for several years with no problemsUses antibody for several years with no problems.
Date published: 2015-04-08
Rated 5 out of 5 by from Good Western blot data of human recombinant ILGood Western blot data of human recombinant IL-13 fusion protein. -SCBT QC
Date published: 2013-05-13
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IL-13 抗体 (F-6) is rated 5.0 out of 5 by 2.
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