Date published: 2025-9-6
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IGFBP7 Antibody (H-3) - Immunohistochemistry - Image 371446
IGFBP7 抗体 (H-3): sc-365293. 福尔马林固定, 石蜡包埋的人输卵管组织的免疫过氧化物酶染色, 显示腺细胞的胞浆染色.
IGFBP7 抗体 (H-3): sc-365293. 福尔马林固定, 石蜡包埋的人输卵管组织的免疫过氧化物酶染色, 显示腺细胞的胞浆染色.

IGFBP7 抗体 (H-3): sc-365293

4.7(7)
寫評論提問

说明书
  • IGFBP7 抗体 H-3 是小鼠单克隆 IgG1 κ，IGFBP7抗体, 在8篇文献中引用，规格为200 µg/ml
  • 免疫human物种的IGFBP7的氨基酸181-282
  • IGFBP7 抗体 (H-3) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 precursor and mature IGFBP7; 也和以下物种反应，包括： 和 equine and bovine
  • 抗IGFBP7抗体（H-3）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IGFBP7 (H-3): sc-365293的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 IGFBP7 抗体 (H-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与IGFBP7 抗体 (H-3) 组合成套装提供。 (请参阅下面的订购信息)。

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相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

此外 IGFBP 抗体 包括 IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, IGFBP6, IGFBP7和IGFBPL1

IGFBP7抗体（H-3）是一种IgG1κ小鼠单克隆IGFBP7抗体（也称为IBP-7抗体、MAC25抗体或PSF抗体），能够通过WB、IP、IF、IHC(P)和ELISA方法检测人类来源的IGFBP7蛋白。IGFBP7抗体（H-3）以非偶联型抗IGFBP7抗体形式供应，同时也提供多种偶联型抗IGFBP7抗体形式，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。胰岛素样生长因子结合蛋白（IGFBPs）是一类与胰岛素样生长因子（IGFs）共同进化的同源蛋白家族。它们不仅作为可溶性IGFs的转运分子，还赋予IGF信号系统一定程度的调节能力。IGFBPs与IGFs的物理结合影响生长因子的生物利用率，以及它们在细胞外环境中的浓度和分布。此外，IGFBPs似乎还具有独立于IGFs的生物活性。已经描述了七种IGFBPs，它们在组织分布、半衰期以及调节IGFs与其受体相互作用方面各不相同。IGFBP-7是一种分泌蛋白，以相对较低的亲和力结合IGF-I和IGF-II。它刺激前列环素（prostacyclin）的产生，并可能作为生长抑制因子发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IGFBP7 抗体 (H-3) 参考文献:

  1. 胰岛素样生长因子结合蛋白作为葡萄糖调节剂。  |  Baxter, RC. 1995. Metabolism. 44: 12-7. PMID: 7476305
  2. IGFBP-1 基因的结构和定位及其在肝脏再生过程中的表达。  |  Lee, J., et al. 1994. Hepatology. 19: 656-65. PMID: 7509771
  3. 胰岛素样生长因子  |  Schmid, C. 1995. Cell Biol Int. 19: 445-57. PMID: 7640658
  4. 调节新陈代谢的 IGF 系统。  |  Binoux, M. 1995. Diabete Metab. 21: 330-7. PMID: 8586149
  5. 正常和增生性疤痕成纤维细胞 IGFBPs 的差异表达。  |  Hathaway, CL., et al. 1996. J Surg Res. 60: 156-62. PMID: 8592408
  6. 胰岛素样生长因子结合蛋白（IGFBPs）及其调控动态。  |  Kelley, KM., et al. 1996. Int J Biochem Cell Biol. 28: 619-37. PMID: 8673727
  7. 胰岛素样生长因子结合蛋白（IGFBP）-7 的合成与特性。重组人 mac25 蛋白可特异性结合 IGF-I 和 -II。  |  Oh, Y., et al. 1996. J Biol Chem. 271: 30322-5. PMID: 8939990

订购信息

产品名称产品编号规格价格数量收藏夹

IGFBP7 抗体 (H-3)

sc-365293
200 µg/ml
$316.00

IGFBP7 (H-3): m-IgGκ BP-HRP 套装

sc-522194
200 µg Ab, 40 µg BP
$354.00

IGFBP7 (H-3): m-IgG1 BP-HRP 套装

sc-533522
200 µg Ab; 20 µg BP
$354.00

IGFBP7 抗体 (H-3) AC

sc-365293 AC
500 µg/ml, 25% agarose
$416.00

IGFBP7 抗体 (H-3) HRP

sc-365293 HRP
200 µg/ml
$316.00

IGFBP7 抗体 (H-3) FITC

sc-365293 FITC
200 µg/ml
$330.00

IGFBP7 抗体 (H-3) PE

sc-365293 PE
200 µg/ml
$343.00

IGFBP7 抗体 (H-3) Alexa Fluor® 488

sc-365293 AF488
200 µg/ml
$357.00

IGFBP7 抗体 (H-3) Alexa Fluor® 546

sc-365293 AF546
200 µg/ml
$357.00

IGFBP7 抗体 (H-3) Alexa Fluor® 594

sc-365293 AF594
200 µg/ml
$357.00

IGFBP7 抗体 (H-3) Alexa Fluor® 647

sc-365293 AF647
200 µg/ml
$357.00

IGFBP7 抗体 (H-3) Alexa Fluor® 680

sc-365293 AF680
200 µg/ml
$357.00

IGFBP7 抗体 (H-3) Alexa Fluor® 790

sc-365293 AF790
200 µg/ml
$357.00

IGFBP7（H-3）抗体可以做COIP吗？

Asked by: Anonymous
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-23

I am using IGFBP7 (H-3): sc-365293 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Germaine
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Works well in WB experimentsWB analysis of IGFBP7 expression in HMEC-1 cell lysate gave specific signal with no background.
Date published: 2021-07-13
Rated 3 out of 5 by from Not very goodTested this antibody in cell lysates and was not able to detect (via western blot) IGFBP7. It works only when i loaded high concentration of proteins
Date published: 2021-01-28
Rated 5 out of 5 by from 抗体很好用！一抗稀释度适中。在人子宫内膜癌细胞HEC-1-B中检测到的条带特异、清晰，几乎没有背景。销售反馈信息很及时。抗体到货迅速，包装非常仔细。
Date published: 2017-05-05
Rated 5 out of 5 by from Versatile AntibodyThis antibody is well-cited for a variety of applications including WB, IP, IF, and even IHC and ELISA. Strong, clear signal with little to no background. Beautiful tissue staining. Works well in a variety of species including equine, bovine, and human samples.
Date published: 2017-01-30
Rated 5 out of 5 by from strong signalThe strong signal with the Western blot in whole cell lysates of CAKI-1, that can be obtained on baseband. Our test had been successful.
Date published: 2017-01-26
Rated 5 out of 5 by from Produced excellent immunoperoxidase strongProduced excellent immunoperoxidase strong cytoplasmic staining in formalin fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date published: 2015-04-11
Rated 5 out of 5 by from Produced positive Western Blot data of IGFBP7Produced positive Western Blot data of IGFBP7 expression in Caki-1 whole cell lysate. -SCBT QC
Date published: 2013-04-16
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IGFBP7 抗体 (H-3) is rated 4.7 out of 5 by 7.
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