Date published: 2025-9-7

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IGFBP2 抗体 (C-10): sc-25285

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说明书
  • IGFBP2 抗体 C-10 是小鼠单克隆 IgG1 κ,IGFBP2抗体, 在10篇文献中引用,规格为200 µg/ml
  • 免疫human物种的insulin-like growth factor binding protein 2 (IGFBP2)的氨基酸1-75
  • IGFBP2 抗体 (C-10) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 IGFBP2
  • 抗IGFBP2抗体(C-10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IGFBP2 (C-10): sc-25285免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是IGFBP2 Antibody (C-10) for WB applications. 的首选辅助检测试剂,这些试剂现与IGFBP2 Antibody (C-10) 打包提供(请参阅下面的订购信息)。

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関連項目

IGFBP2抗体(C-10)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测人类来源的IGFBP2蛋白。IGFBP2 (C-10) 抗体有非结合型和多种结合型可供选择,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。胰岛素样生长因子结合蛋白(IGFBPs)是一组同源蛋白,在调节胰岛素样生长因子(IGFs)在细胞外环境中的生物利用度和活性方面发挥着关键作用。IGFBP2 具有伴侣蛋白的功能,可促进胰岛素样生长因子(IGF)向目标组织的运输,这对于正常生长和发育至关重要。IGFBP2 在包括胎儿眼睛和胎儿大脑在内的各种人体组织中都有表达,这凸显了 IGFBP2 在发育过程中的重要性。IGFBP2 表现出独立于 IGF 的生物活性,进一步强调了 IGFBP2 在细胞信号传导和调节中的多面作用。IGFBP2的多种功能以及与IGFBP3和IGFBP5等其他IGFBPs的相互作用,促成了生长因子调节的复杂网络,使得抗IGFBP2抗体(C-10)成为发育生物学和疾病状态研究的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IGFBP2 抗体 (C-10) 参考文献:

  1. 卵巢癌前体的空间转录组分析揭示了IGFBP2在发病过程中的重新激活。  |  Wang, Y., et al. 2022. Cancer Res. 82: 4528-4541. PMID: 36206311
  2. IGFBP2 的缺失会介导肺泡 2 型细胞衰老并促进肺纤维化。  |  Chin, C., et al. 2023. Cell Rep Med. 4: 100945. PMID: 36787736
  3. 表达IGFBP2的中叶肝细胞优先促进肝脏稳态和再生。  |  Lin, YH., et al. 2023. Cell Stem Cell. 30: 665-676.e4. PMID: 37146585
  4. 乳腺脂肪细胞分泌的IGFBP2限制乳腺癌的侵袭。  |  Conway, JRW., et al. 2023. Sci Adv. 9: eadg1840. PMID: 37436978
  5. 癌相关成纤维细胞相关基因IGFBP2通过诱导M2巨噬细胞分化促进胶质瘤进展。  |  Zhang, X., et al. 2024. Am J Physiol Cell Physiol. 326: C252-C268. PMID: 37982173
  6. 胰岛素样生长因子结合蛋白作为葡萄糖调节剂。  |  Baxter, RC. 1995. Metabolism. 44: 12-7. PMID: 7476305
  7. IGFBP-1 基因的结构和定位及其在肝脏再生过程中的表达。  |  Lee, J., et al. 1994. Hepatology. 19: 656-65. PMID: 7509771
  8. 胰岛素样生长因子  |  Schmid, C. 1995. Cell Biol Int. 19: 445-57. PMID: 7640658
  9. 调节新陈代谢的 IGF 系统。  |  Binoux, M. 1995. Diabete Metab. 21: 330-7. PMID: 8586149
  10. 正常和增生性疤痕成纤维细胞 IGFBPs 的差异表达。  |  Hathaway, CL., et al. 1996. J Surg Res. 60: 156-62. PMID: 8592408
  11. 胰岛素样生长因子结合蛋白(IGFBPs)及其调控动态。  |  Kelley, KM., et al. 1996. Int J Biochem Cell Biol. 28: 619-37. PMID: 8673727
  12. 胰岛素样生长因子结合蛋白(IGFBP)-7 的合成与特性。重组人 mac25 蛋白可特异性结合 IGF-I 和 -II。  |  Oh, Y., et al. 1996. J Biol Chem. 271: 30322-5. PMID: 8939990

订购信息

产品名称产品编号规格价格数量收藏夹

IGFBP2 抗体 (C-10)

sc-25285
200 µg/ml
$316.00

IGFBP2 (C-10): m-IgG Fc BP-HRP 套装

sc-526645
200 µg Ab; 10 µg BP
$354.00

IGFBP2 (C-10): m-IgG1 BP-HRP 套装

sc-532018
200 µg Ab; 20 µg BP
$354.00

IGFBP2 抗体 (C-10) AC

sc-25285 AC
500 µg/ml, 25% agarose
$416.00

IGFBP2 抗体 (C-10) HRP

sc-25285 HRP
200 µg/ml
$316.00

IGFBP2 抗体 (C-10) FITC

sc-25285 FITC
200 µg/ml
$330.00

IGFBP2 抗体 (C-10) PE

sc-25285 PE
200 µg/ml
$343.00

IGFBP2 抗体 (C-10) Alexa Fluor® 488

sc-25285 AF488
200 µg/ml
$357.00

IGFBP2 抗体 (C-10) Alexa Fluor® 546

sc-25285 AF546
200 µg/ml
$357.00

IGFBP2 抗体 (C-10) Alexa Fluor® 594

sc-25285 AF594
200 µg/ml
$357.00

IGFBP2 抗体 (C-10) Alexa Fluor® 647

sc-25285 AF647
200 µg/ml
$357.00

IGFBP2 抗体 (C-10) Alexa Fluor® 680

sc-25285 AF680
200 µg/ml
$357.00

IGFBP2 抗体 (C-10) Alexa Fluor® 790

sc-25285 AF790
200 µg/ml
$357.00

What is the recommended starting dilution for Western blot for sc-25285: IGFBP2 (C-10) monoclonal antibody?

Asked by: Germaine
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 1 out of 5 by from complete no bandsI bought both conjugated and non conjugated antibody. Both my samples and recombinant igfbp2 show no bands at all. But loading control is OK
Date published: 2020-08-25
Rated 1 out of 5 by from Does not work in ELISATwo separate lots of this antibody failed to detection either endogenous (whole cell lysate) or recombinant hIGFBP2. The ELISA designation should be removed.
Date published: 2017-07-27
Rated 5 out of 5 by from Great monoclonal antibodyStrong and specific band with very little background in various samples
Date published: 2017-02-07
Rated 5 out of 5 by from 效果蛮不错的课题组的都觉得报出来效果可以,希望多做些活动,小样赠送什么的都可以呀的。。。。。。。。。。。。。。。
Date published: 2017-01-18
Rated 5 out of 5 by from Worked well in WB in mouse DFWorked well in WB in mouse DF-1 cells. -SCBT Publication Review
Date published: 2015-05-14
Rated 5 out of 5 by from Strong band in WB in T98GStrong band in WB in T98G, MES-SA/Dx5 and MIA PaCa-2 whole cell lysates. -SCBT QC
Date published: 2015-04-08
Rated 5 out of 5 by from Produced publishable data in WB with humanProduced publishable data in WB with human microvascular endothelial cells -SCBT Publication Review
Date published: 2015-03-03
Rated 5 out of 5 by from WB published data with human GBM (U362WB published data with human GBM (U362, YKG-1, Y98G, A172, KS-1, U87, YH-13, U373, and NYGM) -SCBT Publication Review
Date published: 2013-10-02
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IGFBP2 抗体 (C-10) is rated 4.0 out of 5 by 8.
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