IMP-1/IGF2BP1 Antibody (G-8): sc-390149
- IMP-1/IGF2BP1 Antibody (G-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against a peptide mapping within an internal region of IGF2BP1 of human origin
- recommended for detection of IGF2BP1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IMP-1/IGF2BP1 Antibody (G-8) for WB applications. These reagents are now offered in bundles with IMP-1/IGF2BP1 Antibody (G-8) (see ordering information below).
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SEE ALSO...
IGF2BP1 Antibody (G-8) is a mouse monoclonal IgG1 antibody that detects IGF2BP1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IGF2BP1, also known as coding region determinant-binding protein or CRD-BP, plays a crucial role in regulating RNA metabolism and stability, particularly in embryonal tissues where IGF2BP1 is abundantly expressed. IGF2BP1 is integral to the post-transcriptional regulation of several key mRNAs, including those for c-Myc and IGF-II, which are vital for cellular proliferation and growth. The unique structure of IGF2BP1, characterized by a combination of RNA recognition motifs and hnRNP K homology domains, allows IGF2BP1 to bind to specific RNA sequences, thereby influencing their translation and stability. IGF2BP1 is implicated in various cancers, being expressed in a significant percentage of colon cancers, sarcomas, and breast cancers, highlighting IGF2BP1′s potential as a biomarker for tumor progression and a target for therapeutic intervention. The ability of IGF2BP1 to modulate mRNA stability and translation underscores IGF2BP1′s importance in both normal cellular function and disease states, making anti-IGF2BP1 antibody (G-8) a valuable tool for researchers studying RNA-binding proteins and their roles in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IMP-1/IGF2BP1 Antibody (G-8) | sc-390149 | 200 µg/ml | $322.00 | |||
IMP-1/IGF2BP1 Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-540763 | 200 µg Ab; 10 µg BP | $361.00 | |||
IMP-1/IGF2BP1 Antibody (G-8): m-IgG1 BP-HRP Bundle | sc-542355 | 200 µg Ab; 20 µg BP | $361.00 | |||
IMP-1/IGF2BP1 (G-8) Neutralizing Peptide | sc-390149 P | 100 µg/0.5 ml | $69.00 |