HSC70/HSP70 Antibody (B-12): sc-137239
- HSC70/HSP70 Antibody (B-12) is a mouse monoclonal IgG2a λ, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 342-641 mapping at the C-terminus of HSP 70 of human origin
- recommended for detection of HSP 70 and HSC 70 of mouse, rat and human origin by WB, IP, IF and ELISA
- See HSC70/HSP70 (W27): sc-24 for HSC70/HSP70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for HSC70/HSP70 Antibody (B-12) for WB applications. This reagent is now offered in a bundle with HSC70/HSP70 Antibody (B-12) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
HSP 70/HSC 70 Antibody (B-12) is a mouse monoclonal IgG2a antibody that detects HSP 70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HSP 70 is a crucial member of the heat shock protein family, known for its role as a molecular chaperone that assists in the proper folding of nascent polypeptide chains and the prevention of protein aggregation, which is vital for maintaining cellular homeostasis, especially under stress conditions. HSP 70 is predominantly located in the cytosol and nucleus of mammalian cells, where HSP 70 plays a significant role in the cytosolic endoplasmic reticulum and mitochondrial import machinery. HSP 70′s ability to facilitate the translocation of polypeptides across cellular membranes is essential for various cellular processes, including protein synthesis and degradation. Notably, HSP 70 expression is strongly induced in response to heat stress, highlighting HSP 70′s importance in cellular protection mechanisms. HSP 70/HSC 70 (B-12) antibody is an invaluable tool for researchers studying stress responses, protein folding, and the intricate dynamics of cellular protein homeostasis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSC70/HSP70 Antibody (B-12) | sc-137239 | 200 µg/ml | $322.00 | |||
HSC70/HSP70 Antibody (B-12): m-IgGλ BP-HRP Bundle | sc-521466 | 200 µg Ab, 40 µg BP | $361.00 |