HLA-A/B/C Antibody (LY5.1): sc-52810

HLA-A/B/C Antibody (LY5.1) is a mouse monoclonal IgG1 kappa light chain antibody, developed to recognize and bind to human leukocyte antigens HLA-A, HLA-B, and HLA-C, collectively known as MHC class I molecules. These proteins are essential components of the immune system, located on the surface of nearly all nucleated cells where they present endogenous peptide antigens to cytotoxic T lymphocytes, facilitating immune surveillance and the elimination of infected or malignant cells. HLA-A/B/C proteins undergo critical post-translational modifications, including glycosylation, which are crucial for their proper folding, stability, and surface expression, ensuring effective antigen presentation and immune recognition. Anti-HLA-A/B/C antibody (LY5.1) is raised against purified HLA-A/B/C of human origin, providing affinity for these native proteins in their natural conformation. HLA-A/B/C monoclonal antibody (LY5.1) performs in various applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF), making this tool indispensable for researchers studying immune responses, autoimmunity, and transplant compatibility. Anti-HLA-A/B/C antibody (LY5.1) facilitates the investigation of antigen presentation mechanisms and interactions between different immune cells, thereby advancing our understanding of immune regulation and therapeutic development. Studies using HLA-A/B/C monoclonal antibody (LY5.1) to examine post-translational modifications of HLA class I molecules enhance our comprehension of their role in disease progression and immune system function.

The preferred HLA class I antibody is HLA class I Antibody (HP-1F7): sc-69892.