Date published: 2026-6-3

1-800-457-3801

SCBT Portrait Logo
Seach Input

HIV-1 Tat Protein Peptide (CAS 191936-91-1)

0.0(0)
Write a reviewAsk a question

Application:
HIV-1 Tat Protein Peptide is a cell-penetrating peptide used to mediate gene delivery to cells in culture
CAS Number:
191936-91-1
Molecular Weight:
1559.83
Molecular Formula:
C64H118N32O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

HIV-1 Tat Protein Peptide is a synthetic peptide that includes the sequence responsible for the cellular uptake of the human immunodeficiency virus-1 Tat protein, consisting of the polycationic region 49-57. The peptide is part of the protein transduction domain (PTD) and was shown to enable the introduction of nucleic acids into cells. Its primary function involves enhancing the efficiency of viral RNA polymerase II-mediated transcription elongation, a key step in the production of new viral particles. In biochemical and cellular research, the HIV-1 Tat Protein Peptide is often used as a tool to study the mechanisms of transcriptional regulation, RNA polymerase II function, and the intricate interactions between viral proteins and host cellular machinery.


HIV-1 Tat Protein Peptide (CAS 191936-91-1) References

  1. Potential use of non-classical pathways for the transport of macromolecular drugs.  |  Kueltzo, LA. and Middaugh, CR. 2000. Expert Opin Investig Drugs. 9: 2039-50. PMID: 11060791
  2. Stochastic study of the effect of ionic strength on noncovalent interactions in protein pores.  |  Zhao, Q., et al. 2008. Biophys J. 94: 1267-75. PMID: 17993487
  3. Nanopore stochastic detection: diversity, sensitivity, and beyond.  |  Wang, G., et al. 2013. Acc Chem Res. 46: 2867-77. PMID: 23614724
  4. Artificial Cell Membranes Interfaced with Optical Tweezers: A Versatile Microfluidics Platform for Nanomanipulation and Mechanical Characterization.  |  Dols-Perez, A., et al. 2019. ACS Appl Mater Interfaces. 11: 33620-33627. PMID: 31448892
  5. Targeted micelles with chemotherapeutics and gene drugs to inhibit the G1/S and G2/M mitotic cycle of prostate cancer.  |  Zhang, Y., et al. 2021. J Nanobiotechnology. 19: 17. PMID: 33422073

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

HIV-1 Tat Protein Peptide, 0.5 mg

sc-363914
0.5 mg
$77.00

HIV-1 Tat Protein Peptide, 1 mg

sc-363914A
1 mg
$148.00

HIV-1 Tat Protein Peptide, 5 mg

sc-363914B
5 mg
$439.00